{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Medina ND"],"funding":["NINDS NIH HHS"],"pubmed_abstract":["Neuronal intrinsic excitability is a mechanism implicated in learning and memory that is distinct from synaptic plasticity. Prior work in songbirds established that intrinsic properties (IPs) of premotor basal-ganglia-projecting neurons (HVC<sub>X</sub>) relate to learned song. Here we find that temporal song structure is related to specific HVC<sub>X</sub> IPs: HVC<sub>X</sub> from birds who sang longer songs including longer invariant vocalizations (harmonic stacks) had IPs that reflected increased post-inhibitory rebound. This suggests a rebound excitation mechanism underlying the ability of HVC<sub>X</sub> neurons to integrate over long periods of time throughout the song and represent sequence information. To explore this, we constructed a network model of realistic neurons showing ho"],"journal":["bioRxiv : the preprint server for biology"],"pagination":["2024.05.18.594825"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11118566"],"repository":["biostudies-literature"],"pubmed_title":["Bursts from the past: Intrinsic properties link a network model to zebra finch song."],"pmcid":["PMC11118566"],"funding_grant_id":["UF1 NS115821"],"pubmed_authors":["Medina ND","Margoliash D"],"additional_accession":[]},"is_claimable":false,"name":"Bursts from the past: Intrinsic properties link a network model to zebra finch song.","description":"Neuronal intrinsic excitability is a mechanism implicated in learning and memory that is distinct from synaptic plasticity. Prior work in songbirds established that intrinsic properties (IPs) of premotor basal-ganglia-projecting neurons (HVC<sub>X</sub>) relate to learned song. Here we find that temporal song structure is related to specific HVC<sub>X</sub> IPs: HVC<sub>X</sub> from birds who sang longer songs including longer invariant vocalizations (harmonic stacks) had IPs that reflected increased post-inhibitory rebound. This suggests a rebound excitation mechanism underlying the ability of HVC<sub>X</sub> neurons to integrate over long periods of time throughout the song and represent sequence information. To explore this, we constructed a network model of realistic neurons showing ho","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-07-06T03:11:34.4Z","creation":"2026-07-06T03:08:35.477Z"},"accession":"S-EPMC11118566","cross_references":{"pubmed":["38798332"],"doi":["10.1101/2024.05.18.594825"]}}