{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Theys C"],"funding":["Instrumentarium Research Foundation","Royal Society of New Zealand Marsden Fund","NIMH NIH HHS","Sigrid Juselius Foundation","National Institute on Deafness and Other Communication Disorders","University of Turku","Natural Sciences and Engineering Research Council","Kaye Family Research Endowment","Finnish Medical Foundation","National Institutes of Health","Turku University Hospital","NIMH","Simons Foundation Autism Research Initiative","Manley Family","Finnish Parkinson Foundation","NIDCD NIH HHS","NINDS NIH HHS","Health Research Council of New Zealand Charles Hercus Career Development Fellowship","NIH HHS","Ellison/Baszucki Family Foundation"],"pagination":["2203-2213"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11146419"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["147(6)"],"pubmed_abstract":["Stuttering affects approximately 1 in 100 adults and can result in significant communication problems and social anxiety. It most often occurs as a developmental disorder but can also be caused by focal brain damage. These latter cases may lend unique insight into the brain regions causing stuttering. Here, we investigated the neuroanatomical substrate of stuttering using three independent datasets: (i) case reports from the published literature of acquired neurogenic stuttering following stroke (n = 20, 14 males/six females, 16-77 years); (ii) a clinical single study cohort with acquired neurogenic stuttering following stroke (n = 20, 13 males/seven females, 45-87 years); and (iii) adults with persistent developmental stuttering (n = 20, 14 males/six females, 18-43 years). We used the fir"],"journal":["Brain : a journal of neurology"],"pubmed_title":["Localization of stuttering based on causal brain lesions."],"pmcid":["PMC11146419"],"funding_grant_id":["R01 NS127892","K23 MH120510","M1180","K23MH120510","R21MH126271","R21NS123813","R01MH113929","R01 DC007683","R01NS127892","R56AG069086"],"pubmed_authors":["Melzer TR","Theys C","Jaakkola E","De Nil LF","Joutsa J","Guenther FH","Cohen AL","Fox MD"],"additional_accession":[]},"is_claimable":false,"name":"Localization of stuttering based on causal brain lesions.","description":"Stuttering affects approximately 1 in 100 adults and can result in significant communication problems and social anxiety. It most often occurs as a developmental disorder but can also be caused by focal brain damage. These latter cases may lend unique insight into the brain regions causing stuttering. Here, we investigated the neuroanatomical substrate of stuttering using three independent datasets: (i) case reports from the published literature of acquired neurogenic stuttering following stroke (n = 20, 14 males/six females, 16-77 years); (ii) a clinical single study cohort with acquired neurogenic stuttering following stroke (n = 20, 13 males/seven females, 45-87 years); and (iii) adults with persistent developmental stuttering (n = 20, 14 males/six females, 18-43 years). We used the fir","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jun","modification":"2026-06-01T17:29:48.396Z","creation":"2026-04-08T14:18:16.731Z"},"accession":"S-EPMC11146419","cross_references":{"pubmed":["38797521"],"doi":["10.1093/brain/awae059"]}}