{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Pracon R"],"funding":["NCATS NIH HHS","NHLBI NIH HHS"],"pagination":["e013435"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11187765"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(6)"],"pubmed_abstract":["<h4>Background</h4>ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) did not find an overall reduction in cardiovascular events with an initial invasive versus conservative management strategy in chronic coronary disease; however, there were conservative strategy participants who underwent invasive coronary angiography early postrandomization (within 6 months). Identifying factors associated with angiography in conservative strategy participants will inform clinical decision-making in patients with chronic coronary disease.<h4>Methods</h4>Factors independently associated with angiography performed within 6 months of randomization were identified using Fine and Gray proportional subdistribution hazard models, including demographics, regi"],"journal":["Circulation. Cardiovascular interventions"],"pubmed_title":["Factors Associated With Coronary Angiography Performed Within 6 Months of Randomization to the Conservative Strategy in the ISCHEMIA Trial."],"pmcid":["PMC11187765"],"funding_grant_id":["U01 HL105561","U01 HL105907","U01 HL105462","UL1 TR001445","U01 HL105565"],"pubmed_authors":["Matar F","Desire S","Little T","Mull JA","Desimone LA","O'Brien SM","Yun CH","Jaskowiak AJ","Budoff M","Nicollet E","Min Er C","Uchida N","Cheong B","Santana A","Sidhu M","Claudia M","Alfonso MA","Olsowka M","Fletcher G","Juarez B","Khairuddin A","Rocco TP","Qi J","White H","Yu Q","Fontos G","Zambrano Y","Mortara A","Deedwania P","Gevorgyan R","O'Rourke D","Gulati G","Yu Z","Kaczmarska E","Witkowski A","Smith BR","Mishra S","Schoep JJM","Wald R","Gruensfelder S","Zhu B","Zarka A","Selvanayagam JB","Little H","Gagne CE","Laddu AA","Faxon DP","Mishra G","Santos RP","Tarchalski T","Figueiras FP","Mishra M","Mazurek T","Bazeley JW","McFalls EO","Tarantini G","Osseni 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A","Canada S","Barioli A","Pucci G","Ireland KF","Yusnida I","Julian P","Cauthren T","Cohen RA","Mackin A","Esposito G","Salerno WD","Ortuno FM","Loh JP","Banerjee S","El-Hajjar M","Kozlov PS","Gabriel Melo de Barros E Silva P","Parakh N","Figueiredo E","Oliveira NS","Schley A","Sonawane P","Anumpa J","Dekleva MN","O'Neal B","Jimenez M","Jimenez S"],"additional_accession":[]},"is_claimable":false,"name":"Factors Associated With Coronary Angiography Performed Within 6 Months of Randomization to the Conservative Strategy in the ISCHEMIA Trial.","description":"<h4>Background</h4>ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) did not find an overall reduction in cardiovascular events with an initial invasive versus conservative management strategy in chronic coronary disease; however, there were conservative strategy participants who underwent invasive coronary angiography early postrandomization (within 6 months). Identifying factors associated with angiography in conservative strategy participants will inform clinical decision-making in patients with chronic coronary disease.<h4>Methods</h4>Factors independently associated with angiography performed within 6 months of randomization were identified using Fine and Gray proportional subdistribution hazard models, including demographics, regi","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jun","modification":"2026-06-01T16:07:37.56Z","creation":"2026-04-08T14:00:41.347Z"},"accession":"S-EPMC11187765","cross_references":{"pubmed":["38629312"],"doi":["10.1161/circinterventions.123.013435","10.1161/CIRCINTERVENTIONS.123.013435"]}}