biostudies-literatureNi XBNatural Science Foundation of ChinaNatural Science Foundation of Shandong Province, ChinaCAMS Innovation Fund for Medical SciencesNational Natural Science Foundation of China’s Excellent Young Scientists FundState Key Research Development Program of ChinaGuangdong GovernmentHealth and Medical Research FundInnovation and Technology CommissionNational Natural Science Foundation of China's Excellent Young Scientists Fundwrae087https://www.ebi.ac.uk/biostudies/studies/S-EPMC11187987biostudies-literatureUnknown18(1)Spillovers of viruses from animals to humans occur more frequently under warmer conditions, particularly arboviruses. The invasive tick species Haemaphysalis longicornis, the Asian longhorned tick, poses a significant public health threat due to its global expansion and its potential to carry a wide range of pathogens. We analyzed meta-transcriptomic data from 3595 adult H. longicornis ticks collected between 2016 and 2019 in 22 provinces across China encompassing diverse ecological conditions. Generalized additive modeling revealed that climate factors exerted a stronger influence on the virome of H. longicornis than other ecological factors, such as ecotypes, distance to coastline, animal host, tick gender, and antiviral immunity. To understand how climate changes drive the tick virome, The ISME journalEcoclimate drivers shape virome diversity in a globally invasive tick species.PMC11187987D24H, C2i2019YFC12005052019B121205009COVID19022381 621 00582 103 897ZR2020QH2992019-I2M-5-049319220872019YFC1200500Wu YQZhang JCao WCWang GPShum MHLam TTZhao LJia NWang QZhao NQWei HYe YTChen XPierce MPJiang JFCui XMSmith DKSun YFan JLNi XBHe PJWei JTDu LFPei YTick Genome and Microbiome ConsortiumfalseEcoclimate drivers shape virome diversity in a globally invasive tick species.Spillovers of viruses from animals to humans occur more frequently under warmer conditions, particularly arboviruses. The invasive tick species Haemaphysalis longicornis, the Asian longhorned tick, poses a significant public health threat due to its global expansion and its potential to carry a wide range of pathogens. We analyzed meta-transcriptomic data from 3595 adult H. longicornis ticks collected between 2016 and 2019 in 22 provinces across China encompassing diverse ecological conditions. Generalized additive modeling revealed that climate factors exerted a stronger influence on the virome of H. longicornis than other ecological factors, such as ecotypes, distance to coastline, animal host, tick gender, and antiviral immunity. To understand how climate changes drive the tick virome, 2024-01-01T00:00:00Z2024 Jan2026-06-23T03:20:13.074Z2025-04-20T02:20:03.222ZS-EPMC111879873874738910.1093/ismejo/wrae087