{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["22(1)"],"submitter":["Lorentsson HJN"],"funding":["Copenhagen University"],"pubmed_abstract":["<h4>Background and objective</h4>Tuberculosis disease (TB) and tuberculosis infection (TBI) have been associated with increased risk of cardiovascular disease which may be connected to infection-related haemostatic changes. It is unknown if treatment of Mycobacterium tuberculosis influences haemostasis. Here, we assessed if TB or TBI treatment affects thrombelastography (TEG)-assessed haemostasis.<h4>Methods</h4>Individuals with TB or TBI were included from a TB outpatient clinic in Copenhagen, Denmark. Patients treated with antithrombotic medication or systemic immunosuppressants were excluded. TEG analysis was performed before and after TB/TBI treatment using the TEG<sup>®</sup>6s analyser to provide data on the reaction time of clot initiation (R) (min), the speed of clot formation (K) "],"journal":["Thrombosis journal"],"pagination":["54"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11201340"],"repository":["biostudies-literature"],"pubmed_title":["The effect of Mycobacterium tuberculosis treatment on thrombelastography-assessed haemostasis: a prospective cohort study."],"pmcid":["PMC11201340"],"pubmed_authors":["Jensen SG","Clausen CR","Hagelqvist PG","Krogh-Madsen R","Vilsboll T","Knop FK","Johansson PI","Faurholt-Jepsen D","Ravn P","Lorentsson HJN","Hansen KB"],"additional_accession":[]},"is_claimable":false,"name":"The effect of Mycobacterium tuberculosis treatment on thrombelastography-assessed haemostasis: a prospective cohort study.","description":"<h4>Background and objective</h4>Tuberculosis disease (TB) and tuberculosis infection (TBI) have been associated with increased risk of cardiovascular disease which may be connected to infection-related haemostatic changes. It is unknown if treatment of Mycobacterium tuberculosis influences haemostasis. Here, we assessed if TB or TBI treatment affects thrombelastography (TEG)-assessed haemostasis.<h4>Methods</h4>Individuals with TB or TBI were included from a TB outpatient clinic in Copenhagen, Denmark. Patients treated with antithrombotic medication or systemic immunosuppressants were excluded. TEG analysis was performed before and after TB/TBI treatment using the TEG<sup>®</sup>6s analyser to provide data on the reaction time of clot initiation (R) (min), the speed of clot formation (K) ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jun","modification":"2026-06-01T11:31:00.573Z","creation":"2024-10-15T14:37:08.101Z"},"accession":"S-EPMC11201340","cross_references":{"pubmed":["38918780"],"doi":["10.1186/s12959-024-00625-4"]}}