biostudies-literatureUnknown22(1)Lorentsson HJNCopenhagen University<h4>Background and objective</h4>Tuberculosis disease (TB) and tuberculosis infection (TBI) have been associated with increased risk of cardiovascular disease which may be connected to infection-related haemostatic changes. It is unknown if treatment of Mycobacterium tuberculosis influences haemostasis. Here, we assessed if TB or TBI treatment affects thrombelastography (TEG)-assessed haemostasis.<h4>Methods</h4>Individuals with TB or TBI were included from a TB outpatient clinic in Copenhagen, Denmark. Patients treated with antithrombotic medication or systemic immunosuppressants were excluded. TEG analysis was performed before and after TB/TBI treatment using the TEG^®6s analyser to provide data on the reaction time of clot initiation (R) (min), the speed of clot formation (K) Thrombosis journal54https://www.ebi.ac.uk/biostudies/studies/S-EPMC11201340biostudies-literatureThe effect of Mycobacterium tuberculosis treatment on thrombelastography-assessed haemostasis: a prospective cohort study.PMC11201340Jensen SGClausen CRHagelqvist PGKrogh-Madsen RVilsboll TKnop FKJohansson PIFaurholt-Jepsen DRavn PLorentsson HJNHansen KBfalseThe effect of Mycobacterium tuberculosis treatment on thrombelastography-assessed haemostasis: a prospective cohort study.<h4>Background and objective</h4>Tuberculosis disease (TB) and tuberculosis infection (TBI) have been associated with increased risk of cardiovascular disease which may be connected to infection-related haemostatic changes. It is unknown if treatment of Mycobacterium tuberculosis influences haemostasis. Here, we assessed if TB or TBI treatment affects thrombelastography (TEG)-assessed haemostasis.<h4>Methods</h4>Individuals with TB or TBI were included from a TB outpatient clinic in Copenhagen, Denmark. Patients treated with antithrombotic medication or systemic immunosuppressants were excluded. TEG analysis was performed before and after TB/TBI treatment using the TEG^®6s analyser to provide data on the reaction time of clot initiation (R) (min), the speed of clot formation (K) 2024-01-01T00:00:00Z2024 Jun2026-06-01T11:31:00.573Z2024-10-15T14:37:08.101ZS-EPMC112013403891878010.1186/s12959-024-00625-4