{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["46(6)"],"submitter":["Cera N"],"pubmed_abstract":["Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder that affects women of reproductive age, representing the primary cause of anovulatory infertility. The nonapeptide oxytocin (OT) plays an important role in cognitive, emotional, and reproductive functions in human beings. Oxytocin receptors are expressed in several body parts, including the ovaries. Despite this, the possible role played by oxytocin in symptoms of PCOS is not clear. The present systematic review aimed at understanding the presence of possible oxytocin level alterations in PCOS, the connection between alterations of OT levels and the symptoms of PCOS, and the effect of oxytocin administration in PCOS. After a systematic search in the principal databases, eight studies, five human and three animal, were i"],"journal":["Current issues in molecular biology"],"pagination":["5223-5241"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11201948"],"repository":["biostudies-literature"],"pubmed_title":["The Role of Oxytocin in Polycystic Ovary Syndrome: A Systematic Review."],"pmcid":["PMC11201948"],"pubmed_authors":["Pignatelli D","Cera N","Pinto J"],"additional_accession":[]},"is_claimable":false,"name":"The Role of Oxytocin in Polycystic Ovary Syndrome: A Systematic Review.","description":"Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder that affects women of reproductive age, representing the primary cause of anovulatory infertility. The nonapeptide oxytocin (OT) plays an important role in cognitive, emotional, and reproductive functions in human beings. Oxytocin receptors are expressed in several body parts, including the ovaries. Despite this, the possible role played by oxytocin in symptoms of PCOS is not clear. The present systematic review aimed at understanding the presence of possible oxytocin level alterations in PCOS, the connection between alterations of OT levels and the symptoms of PCOS, and the effect of oxytocin administration in PCOS. After a systematic search in the principal databases, eight studies, five human and three animal, were i","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 May","modification":"2026-04-08T19:03:46.708Z","creation":"2025-04-05T17:55:55.271Z"},"accession":"S-EPMC11201948","cross_references":{"pubmed":["38920985"],"doi":["10.3390/cimb46060313"]}}