biostudies-literatureUnknown13(12)Kim EGSesame is an important oilseed crop grown for human consumption in many countries, with a high commercial value due to its high oleic/linoleic acid ratio (O/L ratio). However, its properties may vary among different accessions. In the current study, 282 sesame accessions were evaluated to determine the effects of agronomic traits and genotypes on the O/L ratio. The O/L ratio was positively correlated with the oleic acid (C18:1), stearic acid (C18:0), and myristic acid (C14:0) concentrations, as well as the capsule zone length (CZL), capsule width (CW), and capsule length (CL), and negatively correlated with the linoleic acid (C18:2) and linolenic acid (C18:3) concentrations, the days to maturity (DTM), days to flowering (DTF), and the height of the first capsule-bearing node (HFC) (<i>p</i> < 0.05). In addition, the O/L ratio was affected by the <i>FAD2</i> haplotype, as the Hap2 and Hap3 sesame accessions had lower O/L ratios. Therefore, we suggest that the increase and decrease in the contents of C18:1 and C18:2 are associated with the <i>FAD2</i> haplotype. A total of 25 agronomic traits and fatty acid compositions were compared via statistical analysis, and accessions with a high O/L ratio were selected. The results of this study can be used as a basis for further research on the development of new sesame varieties through enhancing nutritional functionality.Plants (Basel, Switzerland)1590https://www.ebi.ac.uk/biostudies/studies/S-EPMC11207932biostudies-literatureAssociations of the Seed Fatty Acid Composition of Sesame (<i>Sesamum indicum</i> L.) Germplasm with Agronomic Traits and <i>FAD2</i> Variations.PMC11207932Lee SLee JELee GASung JYoo EKim EGYang TJfalseAssociations of the Seed Fatty Acid Composition of Sesame (<i>Sesamum indicum</i> L.) Germplasm with Agronomic Traits and <i>FAD2</i> Variations.Sesame is an important oilseed crop grown for human consumption in many countries, with a high commercial value due to its high oleic/linoleic acid ratio (O/L ratio). However, its properties may vary among different accessions. In the current study, 282 sesame accessions were evaluated to determine the effects of agronomic traits and genotypes on the O/L ratio. The O/L ratio was positively correlated with the oleic acid (C18:1), stearic acid (C18:0), and myristic acid (C14:0) concentrations, as well as the capsule zone length (CZL), capsule width (CW), and capsule length (CL), and negatively correlated with the linoleic acid (C18:2) and linolenic acid (C18:3) concentrations, the days to maturity (DTM), days to flowering (DTF), and the height of the first capsule-bearing node (HFC) (<i>p</i> < 0.05). In addition, the O/L ratio was affected by the <i>FAD2</i> haplotype, as the Hap2 and Hap3 sesame accessions had lower O/L ratios. Therefore, we suggest that the increase and decrease in the contents of C18:1 and C18:2 are associated with the <i>FAD2</i> haplotype. A total of 25 agronomic traits and fatty acid compositions were compared via statistical analysis, and accessions with a high O/L ratio were selected. The results of this study can be used as a basis for further research on the development of new sesame varieties through enhancing nutritional functionality.2024-01-01T00:00:00Z2024 Jun2026-06-27T03:16:57.728Z2026-06-27T03:06:23.271ZS-EPMC112079323893102210.3390/plants13121590