{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Min JG"],"funding":["Korea Institute of Marine Science and Technology Promotion"],"pagination":["680"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11209460"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(6)"],"pubmed_abstract":["Red seabream iridovirus (RSIV) is a major cause of marine fish mortality in Korea, with no effective vaccine available since its first occurrence in the 1990s. This study evaluated the efficacy of a formalin-killed vaccine against RSIV in rock bream under laboratory and field conditions. For the field trial, a total of 103,200 rock bream from two commercial marine cage-cultured farms in Southern Korea were vaccinated. Farm A vaccinated 31,100 fish in July 2020 and monitored them for 18 weeks, while farm B vaccinated 30,700 fish in August 2020 and monitored them for 12 weeks. At farm A, where there was no RSIV infection, the vaccine efficacy was assessed in the lab, showing a relative percentage of survival (RPS) ranging from 40% to 80%. At farm B, where natural RSIV infections occurred, cu"],"journal":["Vaccines"],"pubmed_title":["Evaluation of Formalin-Inactivated Vaccine Efficacy against Red Seabream Iridovirus (RSIV) in Laboratory and Field Conditions."],"pmcid":["PMC11209460"],"funding_grant_id":["00236096"],"pubmed_authors":["Kim CH","Min JG","Kim GH","Kwon WJ","Kim KI","Jeong HD"],"additional_accession":[]},"is_claimable":false,"name":"Evaluation of Formalin-Inactivated Vaccine Efficacy against Red Seabream Iridovirus (RSIV) in Laboratory and Field Conditions.","description":"Red seabream iridovirus (RSIV) is a major cause of marine fish mortality in Korea, with no effective vaccine available since its first occurrence in the 1990s. This study evaluated the efficacy of a formalin-killed vaccine against RSIV in rock bream under laboratory and field conditions. For the field trial, a total of 103,200 rock bream from two commercial marine cage-cultured farms in Southern Korea were vaccinated. Farm A vaccinated 31,100 fish in July 2020 and monitored them for 18 weeks, while farm B vaccinated 30,700 fish in August 2020 and monitored them for 12 weeks. At farm A, where there was no RSIV infection, the vaccine efficacy was assessed in the lab, showing a relative percentage of survival (RPS) ranging from 40% to 80%. At farm B, where natural RSIV infections occurred, cu","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jun","modification":"2026-04-07T22:48:39.366Z","creation":"2025-04-04T21:22:23.963Z"},"accession":"S-EPMC11209460","cross_references":{"pubmed":["38932409"],"doi":["10.3390/vaccines12060680"]}}