biostudies-literatureHong JHMinistry of Science and Technology, Taiwan587-599https://www.ebi.ac.uk/biostudies/studies/S-EPMC11216962biostudies-literatureUnknown42(3)<h4>Purpose</h4>Active surveillance (AS) is one of the management options for patients with low-risk and select intermediate-risk prostate cancer (PC). However, factors predicting disease reclassification and conversion to active treatment from a large population of pure Asian cohorts regarding AS are less evaluated. This study investigated the intermediate-term outcomes of patients with localized PC undergoing AS.<h4>Materials and methods</h4>This cohort study enrolled consecutive men with localized non-high-risk PC diagnosed in Taiwan between June 2012 and Jan 2023. The study endpoints were disease reclassification (either pathological or radiographic progression) and conversion to active treatment. The factors predicting endpoints were evaluated using the Cox proportional hazards model.The world journal of men's healthActive Surveillance for Taiwanese Men with Localized Prostate Cancer: Intermediate-Term Outcomes and Predictive Factors.PMC11216962MOST 108-2314-B-002-079-MY3MOST 108–2314-B-002–079-MY3MOST 107-2314-B-002-032-MY3Huang KHLu YCHong JHHuang CYLiu SPChueh SJPu YSChow PMChen CHKuo MCCheng YTfalseActive Surveillance for Taiwanese Men with Localized Prostate Cancer: Intermediate-Term Outcomes and Predictive Factors.<h4>Purpose</h4>Active surveillance (AS) is one of the management options for patients with low-risk and select intermediate-risk prostate cancer (PC). However, factors predicting disease reclassification and conversion to active treatment from a large population of pure Asian cohorts regarding AS are less evaluated. This study investigated the intermediate-term outcomes of patients with localized PC undergoing AS.<h4>Materials and methods</h4>This cohort study enrolled consecutive men with localized non-high-risk PC diagnosed in Taiwan between June 2012 and Jan 2023. The study endpoints were disease reclassification (either pathological or radiographic progression) and conversion to active treatment. The factors predicting endpoints were evaluated using the Cox proportional hazards model.2024-01-01T00:00:00Z2024 Jul2025-04-04T19:23:16.07Z2025-04-04T19:23:16.07ZS-EPMC112169623785353410.5534/wjmh.230107