{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Talenti A"],"funding":["Foreign and Commonwealth Office","RCUK | Biotechnology and Biological Sciences Research Council","Foreign and Commonwealth Office (FCO)","Bill and Melinda Gates Foundation","Wellcome Trust","Biotechnology and Biological Sciences Research Council","Bill and Melinda Gates Foundation (Bill & Melinda Gates Foundation)"],"pagination":["792"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11217449"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(1)"],"pubmed_abstract":["The African buffalo (Syncerus caffer) is a wild bovid with a historical distribution across much of sub-Saharan Africa. Genomic analysis can provide insights into the evolutionary history of the species, and the key selective pressures shaping populations, including assessment of population level differentiation, population fragmentation, and population genetic structure. In this study we generated the highest quality de novo genome assembly (2.65 Gb, scaffold N50 69.17 Mb) of African buffalo to date, and sequenced a further 195 genomes from across the species distribution. Principal component and admixture analyses provided little support for the currently described four subspecies. Estimating Effective Migration Surfaces analysis suggested that geographical barriers have played a signifi"],"journal":["Communications biology"],"pubmed_title":["Continent-wide genomic analysis of the African buffalo (Syncerus caffer)."],"pmcid":["PMC11217449"],"funding_grant_id":["BB/S020152/1","BBS/E/D/20002174","BBS/E/D/20002172","BBS/E/D/10002070","WT222155/Z/20/Z","BBS/OS/GC/000012C","OPP1127286"],"pubmed_authors":["Mutinda M","Ngulu SD","Smitz N","Prendergast JGD","Hemmink JD","Chardonnet P","Michaux J","Lembo T","Bishop RP","Auty HK","Atimnedi P","Mramba F","Hourlier T","Paxton E","Nanteza A","Labuschagne M","Morrison LJ","Cornelis D","Fyumagwa R","Jayaraman S","Cook EA","Wilkinson T","Martin FJ","Obara I","Caron A","Robert C","Keyyu JD","Talenti A","Toye P","Garcia Giron C"],"additional_accession":[]},"is_claimable":false,"name":"Continent-wide genomic analysis of the African buffalo (Syncerus caffer).","description":"The African buffalo (Syncerus caffer) is a wild bovid with a historical distribution across much of sub-Saharan Africa. Genomic analysis can provide insights into the evolutionary history of the species, and the key selective pressures shaping populations, including assessment of population level differentiation, population fragmentation, and population genetic structure. In this study we generated the highest quality de novo genome assembly (2.65 Gb, scaffold N50 69.17 Mb) of African buffalo to date, and sequenced a further 195 genomes from across the species distribution. Principal component and admixture analyses provided little support for the currently described four subspecies. Estimating Effective Migration Surfaces analysis suggested that geographical barriers have played a signifi","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jun","modification":"2026-06-02T22:49:21.711Z","creation":"2025-04-04T12:21:57.421Z"},"accession":"S-EPMC11217449","cross_references":{"pubmed":["38951693"],"doi":["10.1038/s42003-024-06481-2"]}}