biostudies-literatureYang Xthe real-world study of recurrent pregnancy loss in Chinathe Medical Innovation and Development Project of Lanzhou University381https://www.ebi.ac.uk/biostudies/studies/S-EPMC11218098biostudies-literatureUnknown24(1)<h4>Background</h4>For women who have experienced recurrent pregnancy loss (RPL), it is crucial not only to treat them but also to evaluate the risk of recurrence. The study aimed to develop a risk predictive model to predict the subsequent early pregnancy loss (EPL) in women with RPL based on preconception data.<h4>Methods</h4>A prospective, dynamic population cohort study was carried out at the Second Hospital of Lanzhou University. From September 2019 to December 2022, a total of 1050 non-pregnant women with RPL were participated. By December 2023, 605 women had subsequent pregnancy outcomes and were randomly divided into training and validation group by 3:1 ratio. In the training group, univariable screening was performed on RPL patients with subsequent EPL outcome. The least absolute BMC women's healthPredicting risk of the subsequent early pregnancy loss in women with recurrent pregnancy loss based on preconception data.PMC11218098lzuyxcx-2022-137YJS-BD-19Yang XZhang WYang YWang RWang FfalsePredicting risk of the subsequent early pregnancy loss in women with recurrent pregnancy loss based on preconception data.<h4>Background</h4>For women who have experienced recurrent pregnancy loss (RPL), it is crucial not only to treat them but also to evaluate the risk of recurrence. The study aimed to develop a risk predictive model to predict the subsequent early pregnancy loss (EPL) in women with RPL based on preconception data.<h4>Methods</h4>A prospective, dynamic population cohort study was carried out at the Second Hospital of Lanzhou University. From September 2019 to December 2022, a total of 1050 non-pregnant women with RPL were participated. By December 2023, 605 women had subsequent pregnancy outcomes and were randomly divided into training and validation group by 3:1 ratio. In the training group, univariable screening was performed on RPL patients with subsequent EPL outcome. The least absolute 2024-01-01T00:00:00Z2024 Jul2025-04-04T12:54:21.575Z2025-04-04T12:54:21.575ZS-EPMC112180983895662710.1186/s12905-024-03206-9