biostudies-literatureDogra NNEI NIH HHSCenter of ExcellenceEnVision LLCCenter of Emerging and Innovative Science for Empire State DevelopmentNational Eye Institute and Office of Behavioral and Social Sciences ResearchResearch to Prevent Blindnesse3582https://www.ebi.ac.uk/biostudies/studies/S-EPMC11219293biostudies-literatureUnknown14(7)<h4>Background/objectives</h4>Stroke damage to the primary visual cortex induces large, homonymous visual field defects that impair daily living. Here, we asked if vision-related quality of life (VR-QoL) is impacted by time since stroke.<h4>Subjects/methods</h4>We conducted a retrospective meta-analysis of 95 occipital stroke patients (female/male = 26/69, 27-78 years old, 0.5-373.5 months poststroke) in whom VR-QoL was estimated using the National Eye Institute Visual Functioning Questionnaire (NEI-VFQ) and its 10-item neuro-ophthalmic supplement (Neuro10). Visual deficit severity was represented by the perimetric mean deviation (PMD) calculated from 24-2 Humphrey visual fields. Data were compared with published cohorts of visually intact controls. The relationship between VR-QoL and timeBrain and behaviorVision-related quality of life after unilateral occipital stroke.PMC11219293R01 EY027314P30 EY001319R01 EY027314-05S1R01 EY027314-05S21689bC2T32 EY0071251730C004Lilley SJohnson BAYang JRedmond BVCavanaugh MRDogra NLam BLTamhankar MHuxlin KRFahrenthold BFeldon SEfalseVision-related quality of life after unilateral occipital stroke.<h4>Background/objectives</h4>Stroke damage to the primary visual cortex induces large, homonymous visual field defects that impair daily living. Here, we asked if vision-related quality of life (VR-QoL) is impacted by time since stroke.<h4>Subjects/methods</h4>We conducted a retrospective meta-analysis of 95 occipital stroke patients (female/male = 26/69, 27-78 years old, 0.5-373.5 months poststroke) in whom VR-QoL was estimated using the National Eye Institute Visual Functioning Questionnaire (NEI-VFQ) and its 10-item neuro-ophthalmic supplement (Neuro10). Visual deficit severity was represented by the perimetric mean deviation (PMD) calculated from 24-2 Humphrey visual fields. Data were compared with published cohorts of visually intact controls. The relationship between VR-QoL and time2024-01-01T00:00:00Z2024 Jul2026-07-15T08:23:15.09Z2025-04-04T12:20:34.574ZS-EPMC112192933895681310.1002/brb3.3582