biostudies-literatureUnknown14(1)Park HGC biopharmaInbody co.To treat hypovolemic shock, fluid infusion or blood transfusion is essential to address insufficient volume. Much controversy surrounds resuscitation in hypovolemic shock. We aimed to identify the ideal fluid combination for treating hypovolemic shock-induced swine model, analyzing bioelectrical impedance and hemodynamics. Fifteen female three-way crossbred pigs were divided into three different groups. The three resuscitation fluids were (1) balanced crystalloid, (2) balanced crystalloid + 5% dextrose water, and (3) balanced crystalloid + 20% albumin. The experiment was divided into three phases and conducted sequentially: (1) controlled hemorrhage (1 L bleeding, 60 min), (2) resuscitation phase 1 (1 L fluid infusion, 60 min), and (3) resuscitation phase 2 (1 L fluid infusion, 60 min). BiScientific reports15077https://www.ebi.ac.uk/biostudies/studies/S-EPMC11219720biostudies-literatureAnalysis of hemodynamics and impedance using bioelectrical impedance analysis in hypovolemic shock-induced swine model.PMC11219720Park HLee HLee JMBaik SfalseAnalysis of hemodynamics and impedance using bioelectrical impedance analysis in hypovolemic shock-induced swine model.To treat hypovolemic shock, fluid infusion or blood transfusion is essential to address insufficient volume. Much controversy surrounds resuscitation in hypovolemic shock. We aimed to identify the ideal fluid combination for treating hypovolemic shock-induced swine model, analyzing bioelectrical impedance and hemodynamics. Fifteen female three-way crossbred pigs were divided into three different groups. The three resuscitation fluids were (1) balanced crystalloid, (2) balanced crystalloid + 5% dextrose water, and (3) balanced crystalloid + 20% albumin. The experiment was divided into three phases and conducted sequentially: (1) controlled hemorrhage (1 L bleeding, 60 min), (2) resuscitation phase 1 (1 L fluid infusion, 60 min), and (3) resuscitation phase 2 (1 L fluid infusion, 60 min). Bi2024-01-01T00:00:00Z2024 Jul2025-04-04T23:55:39.16Z2025-04-04T23:55:39.16ZS-EPMC112197203895621610.1038/s41598-024-65847-y