{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Knihtila HM"],"funding":["The Paulo Foundation","NIEHS NIH HHS","NIH Office of the Director","NHLBI NIH HHS","National Heart Lung and Blood Institute","Lastentautien Tutkimussäätiö","NIH HHS","Jane and Aatos Erkko Fundation"],"pagination":["94-100.e13"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11227409"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["154(1)"],"pubmed_abstract":["<h4>Background</h4>Asthmatic symptoms often start during early childhood. Impulse oscillometry (IOS) is feasible in preschool children who may be unable to reliably perform spirometry measurements.<h4>Objective</h4>We sought to evaluate the use of IOS in a multicenter, multiethnic high-risk asthma cohort titled the Vitamin D Antenatal Asthma Reduction Trial.<h4>Methods</h4>The trial recruited pregnant women whose children were followed from birth to age 8 years. Lung function was assessed with IOS at ages 4, 5, and 6 years and spirometry at ages 5, 6, 7, and 8 years. Asthma status, respiratory symptoms, and medication use were assessed with repeated questionnaires from birth to age 8 years.<h4>Results</h4>In total, 220 children were included in this secondary analysis. Recent respiratory s"],"journal":["The Journal of allergy and clinical immunology"],"pubmed_title":["Preschool impulse oscillometry predicts active asthma and impaired lung function at school age."],"pmcid":["PMC11227409"],"funding_grant_id":["R01 HL091528","P30 ES001247","UH3 OD023268"],"pubmed_authors":["Knihtila HM","Zeiger RS","Laranjo N","Bacharier LB","Litonjua AA","Carey VJ","O'Connor GT","Weiss ST","Stubbs BJ"],"additional_accession":[]},"is_claimable":false,"name":"Preschool impulse oscillometry predicts active asthma and impaired lung function at school age.","description":"<h4>Background</h4>Asthmatic symptoms often start during early childhood. Impulse oscillometry (IOS) is feasible in preschool children who may be unable to reliably perform spirometry measurements.<h4>Objective</h4>We sought to evaluate the use of IOS in a multicenter, multiethnic high-risk asthma cohort titled the Vitamin D Antenatal Asthma Reduction Trial.<h4>Methods</h4>The trial recruited pregnant women whose children were followed from birth to age 8 years. Lung function was assessed with IOS at ages 4, 5, and 6 years and spirometry at ages 5, 6, 7, and 8 years. Asthma status, respiratory symptoms, and medication use were assessed with repeated questionnaires from birth to age 8 years.<h4>Results</h4>In total, 220 children were included in this secondary analysis. Recent respiratory s","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2026-06-02T20:29:04.827Z","creation":"2026-04-20T03:10:05.884Z"},"accession":"S-EPMC11227409","cross_references":{"pubmed":["38244724"],"doi":["10.1016/j.jaci.2023.12.025"]}}