{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang P"],"funding":["National Aeronautics and Space Administration (NASA)","Center for Hierarchical Manufacturing, National Science Foundation (Center for Hierarchical Manufacturing)","National Aeronautics and Space Administration","Center for Hierarchical Manufacturing, National Science Foundation","John Templeton Foundation"],"pagination":["825"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11227552"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(1)"],"pubmed_abstract":["Convergent evolution is central in the origins of multicellularity. Identifying the basis for convergent multicellular evolution is challenging because of the diverse evolutionary origins and environments involved. Haploid Kluyveromyces lactis populations evolve multicellularity during selection for increased settling in liquid media. Strong genomic and phenotypic convergence is observed between K. lactis and previously selected S. cerevisiae populations under similar selection, despite their >100-million-year divergence. We find K. lactis multicellularity is conferred by mutations in genes ACE2 or AIM44, with ACE2 being predominant. They are a subset of the six genes involved in the S. cerevisiae multicellularity. Both ACE2 and AIM44 regulate cell division, indicating that the genetic con"],"journal":["Communications biology"],"pubmed_title":["Genomic sequencing reveals convergent adaptation during experimental evolution in two budding yeast species."],"pmcid":["PMC11227552"],"funding_grant_id":["16-IDEAS16-0002","1724011"],"pubmed_authors":["Wang P","Driscoll WW","Travisano M"],"additional_accession":[]},"is_claimable":false,"name":"Genomic sequencing reveals convergent adaptation during experimental evolution in two budding yeast species.","description":"Convergent evolution is central in the origins of multicellularity. Identifying the basis for convergent multicellular evolution is challenging because of the diverse evolutionary origins and environments involved. Haploid Kluyveromyces lactis populations evolve multicellularity during selection for increased settling in liquid media. Strong genomic and phenotypic convergence is observed between K. lactis and previously selected S. cerevisiae populations under similar selection, despite their >100-million-year divergence. We find K. lactis multicellularity is conferred by mutations in genes ACE2 or AIM44, with ACE2 being predominant. They are a subset of the six genes involved in the S. cerevisiae multicellularity. Both ACE2 and AIM44 regulate cell division, indicating that the genetic con","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2025-04-22T15:37:36.832Z","creation":"2025-04-06T01:24:56.298Z"},"accession":"S-EPMC11227552","cross_references":{"pubmed":["38971878"],"doi":["10.1038/s42003-024-06485-y"]}}