{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Slaughter JL"],"funding":["NHLBI NIH HHS","NINDS NIH HHS","National Heart, Lung, and Blood Institute, National Institutes of Health","NIH HHS"],"pagination":["495-504"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11228129"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["38(6)"],"pubmed_abstract":["<h4>Background</h4>Off-label treatment of extremely preterm infants with diuretics and inhaled corticosteroids (ICS) for evolving bronchopulmonary dysplasia (BPD) is common. Their effectiveness in reducing mortality or BPD severity, and optimal treatment timing, are unclear.<h4>Objectives</h4>To determine whether diuretic treatment or ICS administration for infants with early evolving (between 10-27 days postnatal) and progressively evolving (28th-day-36th-week postnatal) BPD are independently associated with reduced mortality and moderate or severe BPD at 36-weeks postmenstrual age (PMA).<h4>Methods</h4>We examined neonates born before 28 weeks' gestation and admitted to neonatal intensive care units on postnatal Day 0 between 2006 and 2016 using data collected during routine care recorde"],"journal":["Paediatric and perinatal epidemiology"],"pubmed_title":["Estimating the effect of diuretics and inhaled corticosteroids for evolving bronchopulmonary dysplasia in preterm infants."],"pmcid":["PMC11228129"],"funding_grant_id":["UG3 NS117844","UG3 OD035536","R01 HL145032","R03 HL140272","UH3 HL161338"],"pubmed_authors":["Klebanoff MA","Hade EM","Slaughter JL"],"additional_accession":[]},"is_claimable":false,"name":"Estimating the effect of diuretics and inhaled corticosteroids for evolving bronchopulmonary dysplasia in preterm infants.","description":"<h4>Background</h4>Off-label treatment of extremely preterm infants with diuretics and inhaled corticosteroids (ICS) for evolving bronchopulmonary dysplasia (BPD) is common. Their effectiveness in reducing mortality or BPD severity, and optimal treatment timing, are unclear.<h4>Objectives</h4>To determine whether diuretic treatment or ICS administration for infants with early evolving (between 10-27 days postnatal) and progressively evolving (28th-day-36th-week postnatal) BPD are independently associated with reduced mortality and moderate or severe BPD at 36-weeks postmenstrual age (PMA).<h4>Methods</h4>We examined neonates born before 28 weeks' gestation and admitted to neonatal intensive care units on postnatal Day 0 between 2006 and 2016 using data collected during routine care recorde","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Aug","modification":"2026-03-18T13:24:05.48Z","creation":"2025-08-18T09:54:04.784Z"},"accession":"S-EPMC11228129","cross_references":{"pubmed":["38192005"],"doi":["10.1111/ppe.13038"]}}