biostudies-literatureUnknown17(1)Cooper D<h4>Background</h4>The incidence of hypothyroidism following hemithyroidectomy and risk factors associated with its occurrence are not completely understood. This systematic review investigated the incidence and risk factors for hypothyroidism, thyroxine supplementation following hemithyroidectomy as well as the course of post-operative hypothyroidism, including the time to hypothyroidism and incidence of transient hypothyroidism.<h4>Methods</h4>Searches were conducted in MEDLINE, EMBASE, Scopus, and Cochrane library for studies reporting the incidence of hypothyroidism or thyroxine supplementation following hemithyroidectomy.<h4>Results</h4>Sixty-six studies were eligible for inclusion: 36 reported risk factors, and 27 reported post-operative course of hypothyroidism. Median follow-up wasThyroid research18https://www.ebi.ac.uk/biostudies/studies/S-EPMC11229296biostudies-literatureHypothyroidism after hemithyroidectomy: a systematic review and meta-analysis.PMC11229296Ayeni FEEslick GDCooper DEdirimanne SKaur RfalseHypothyroidism after hemithyroidectomy: a systematic review and meta-analysis.<h4>Background</h4>The incidence of hypothyroidism following hemithyroidectomy and risk factors associated with its occurrence are not completely understood. This systematic review investigated the incidence and risk factors for hypothyroidism, thyroxine supplementation following hemithyroidectomy as well as the course of post-operative hypothyroidism, including the time to hypothyroidism and incidence of transient hypothyroidism.<h4>Methods</h4>Searches were conducted in MEDLINE, EMBASE, Scopus, and Cochrane library for studies reporting the incidence of hypothyroidism or thyroxine supplementation following hemithyroidectomy.<h4>Results</h4>Sixty-six studies were eligible for inclusion: 36 reported risk factors, and 27 reported post-operative course of hypothyroidism. Median follow-up was2024-01-01T00:00:00Z2024 Jul2025-04-04T11:24:40.818Z2025-04-04T11:24:40.818ZS-EPMC112292963897298710.1186/s13044-024-00200-z