biostudies-literatureUnknown271(7)Maida EUniversità degli Studi della Campania Luigi Vanvitelli<h4>Background</h4>ChatGPT is an open-source natural language processing software that replies to users' queries. We conducted a cross-sectional study to assess people living with Multiple Sclerosis' (PwMS) preferences, satisfaction, and empathy toward two alternate responses to four frequently-asked questions, one authored by a group of neurologists, the other by ChatGPT.<h4>Methods</h4>An online form was sent through digital communication platforms. PwMS were blind to the author of each response and were asked to express their preference for each alternate response to the four questions. The overall satisfaction was assessed using a Likert scale (1-5); the Consultation and Relational Empathy scale was employed to assess perceived empathy.<h4>Results</h4>We included 1133 PwMS (age, 45.26 Journal of neurology4057-4066https://www.ebi.ac.uk/biostudies/studies/S-EPMC11233331biostudies-literatureChatGPT vs. neurologists: a cross-sectional study investigating preference, satisfaction ratings and perceived empathy in responses among people living with multiple sclerosis.PMC11233331Bonavita SDigital Technologies, Web, Social Media Study Group of the Italian Society of Neurology (SIN)Spiezia ALCorea FLeocani LDe Stefano NLeone MSacco SScandurra CIanniello AFoschi MLavorgna LCocco EAffinito GLauro FMiele GMaida EFerraro DDocimo RTrojsi FFrau JSmolik KGabriele FSparaco MPadovani ACoghe GTriassi MMancinelli LLorusso LAbbadessa GMorra VBMoccia MInglese MDi Sapio ACarotenuto AStromillo MLBorriello GRepice AMLeveraro EBile FStreito LMDe Martino ARomoli MPalladino RDe Santis FClerico MMarinelli FBisecco AIodice RLanzillo RfalseChatGPT vs. neurologists: a cross-sectional study investigating preference, satisfaction ratings and perceived empathy in responses among people living with multiple sclerosis.<h4>Background</h4>ChatGPT is an open-source natural language processing software that replies to users' queries. We conducted a cross-sectional study to assess people living with Multiple Sclerosis' (PwMS) preferences, satisfaction, and empathy toward two alternate responses to four frequently-asked questions, one authored by a group of neurologists, the other by ChatGPT.<h4>Methods</h4>An online form was sent through digital communication platforms. PwMS were blind to the author of each response and were asked to express their preference for each alternate response to the four questions. The overall satisfaction was assessed using a Likert scale (1-5); the Consultation and Relational Empathy scale was employed to assess perceived empathy.<h4>Results</h4>We included 1133 PwMS (age, 45.26 2024-01-01T00:00:00Z2024 Jul2025-04-04T11:25:00.373Z2025-04-04T11:25:00.373ZS-EPMC112333313856822710.1007/s00415-024-12328-x