{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Peyre M"],"funding":["French CRC","French national PHRC"],"pagination":["e16211"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11235986"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["31(5)"],"pubmed_abstract":["<h4>Background</h4>Nonreversible hearing loss (HL) is the main sequelae of Susac syndrome (SuS). We aimed to identify risk factors for HL in SuS.<h4>Methods</h4>The CARESS study is a prospective national cohort study that started in December 2011, including all consecutive patients with SuS referred to the French reference center. The CARESS study was designed with a follow-up including fundoscopy, audiometry, and brain magnetic resonance imaging at 1, 3, 6, and 12 months after diagnosis and then annually for 5 years. The primary outcome was the occurrence at last follow-up of severe HL defined as the loss of 70 dB in at least one ear on audiometry or the need for hearing aids.<h4>Results</h4>Thirty-six patients (female 66.7%, median age 37.5 [range 24.5-42.5] years) included in the clinic"],"journal":["European journal of neurology"],"pubmed_title":["Risk factors for severe hearing loss in Susac syndrome: A national cohort study."],"pmcid":["PMC11235986"],"funding_grant_id":["P081261","CRC19059"],"pubmed_authors":["Sacre K","French Susac Study Group","Halimi C","Turc G","Debruxelles S","Papo T","Capron J","Peyre M","Lapergue B","Mageau A","Mohamed S","Rouzaud D","de Brouker T","Henry Feugeas MC","Doan S","Hamidou M","Laouenan C","Francois C","Delory N","Godard-Ducceschi S","Grosset-Janin D","Le Quellec A","Mouthon L","Chauveheid MP","Goulenok T","Noury JB","Beldjoudi N","Klein I","Alexandra JF","Farhi F","Bodenant M","Godeau B","Aumaitre O","Wacongne A","de Bustos EM","Ellie E","Dossier A"],"additional_accession":[]},"is_claimable":false,"name":"Risk factors for severe hearing loss in Susac syndrome: A national cohort study.","description":"<h4>Background</h4>Nonreversible hearing loss (HL) is the main sequelae of Susac syndrome (SuS). We aimed to identify risk factors for HL in SuS.<h4>Methods</h4>The CARESS study is a prospective national cohort study that started in December 2011, including all consecutive patients with SuS referred to the French reference center. The CARESS study was designed with a follow-up including fundoscopy, audiometry, and brain magnetic resonance imaging at 1, 3, 6, and 12 months after diagnosis and then annually for 5 years. The primary outcome was the occurrence at last follow-up of severe HL defined as the loss of 70 dB in at least one ear on audiometry or the need for hearing aids.<h4>Results</h4>Thirty-six patients (female 66.7%, median age 37.5 [range 24.5-42.5] years) included in the clinic","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 May","modification":"2026-06-02T22:12:52.301Z","creation":"2025-04-19T13:13:44.93Z"},"accession":"S-EPMC11235986","cross_references":{"pubmed":["38235955"],"doi":["10.1111/ene.16211"]}}