{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Khalil M"],"funding":["NCI NIH HHS"],"pagination":["5283-5292"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11236845"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["31(8)"],"pubmed_abstract":["<h4>Background</h4>New persistent opioid use (NPOU) after surgery has been identified as a common complication. This study sought to assess the long-term health outcomes among patients who experienced NPOU after gastrointestinal (GI) cancer surgery.<h4>Methods</h4>Patients who underwent surgery for hepato-pancreato-biliary and colorectal cancer between 2007 and 2019 were identified using the Surveillance, Epidemiology, and End Results (SEER)-Medicare-linked database. Mixed-effect multivariable logistic regression and Cox proportional hazard models were used to estimate the risk of mortality and hospital visits related to falls, respiratory events, or pain symptoms.<h4>Results</h4>Among 15,456 patients who underwent GI cancer surgery, 967(6.6%) experienced NPOU. Notably, the patients at ris"],"journal":["Annals of surgical oncology"],"pubmed_title":["Long-term Health Outcomes of New Persistent Opioid Use After Gastrointestinal Cancer Surgery."],"pmcid":["PMC11236845"],"funding_grant_id":["HHSN261201800032I","HHSN261201800009C","HHSN261201800009I","HHSN261201800015C","HHSN261201800032C","HHSN261201800015I"],"pubmed_authors":["Khalil M","Woldesenbet S","Khan MMM","Tsai S","Munir MM","Endo Y","Rashid Z","Dillhoff M","Altaf A","Katayama E","Pawlik TM"],"additional_accession":[]},"is_claimable":false,"name":"Long-term Health Outcomes of New Persistent Opioid Use After Gastrointestinal Cancer Surgery.","description":"<h4>Background</h4>New persistent opioid use (NPOU) after surgery has been identified as a common complication. This study sought to assess the long-term health outcomes among patients who experienced NPOU after gastrointestinal (GI) cancer surgery.<h4>Methods</h4>Patients who underwent surgery for hepato-pancreato-biliary and colorectal cancer between 2007 and 2019 were identified using the Surveillance, Epidemiology, and End Results (SEER)-Medicare-linked database. Mixed-effect multivariable logistic regression and Cox proportional hazard models were used to estimate the risk of mortality and hospital visits related to falls, respiratory events, or pain symptoms.<h4>Results</h4>Among 15,456 patients who underwent GI cancer surgery, 967(6.6%) experienced NPOU. Notably, the patients at ris","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Aug","modification":"2025-04-19T01:04:27.866Z","creation":"2025-04-07T12:02:35.154Z"},"accession":"S-EPMC11236845","cross_references":{"pubmed":["38762641"],"doi":["10.1245/s10434-024-15435-1"]}}