{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sun R-Y"],"funding":["Research Grants Council of the Hong Kong Special Administrative Region, China","Innovation Team Project of Guangdong University","National Natural Science Foundation of China","Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program"],"pagination":["e0116423"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11237462"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(6)"],"pubmed_abstract":["<i>Salmonella</i> 4,[5],12:i:-, a monophasic variant of <i>Salmonella</i> Typhimurium, has emerged as a global cause of multidrug-resistant salmonellosis and has become endemic in many developing and developed countries, especially in China. Here, we have sequenced 352 clinical isolates in Guangdong, China, during 2009-2019 and performed a large-scale collection of <i>Salmonella</i> 4,[5],12:i:- with whole genome sequencing (WGS) data across the globe, to better understand the population structure, antimicrobial resistance (AMR) genomic characterization, and transmission routes of <i>Salmonella</i> 4,[5],12:i:- across Guangdong. <i>Salmonella</i> 4,[5],12:i:- strains showed broad genetic diversity; Guangdong isolates were found to be widely distributed among the global lineages. Of note, w"],"journal":["mSystems"],"pubmed_title":["Antimicrobial resistance and population genomics of emerging multidrug-resistant <i>Salmonella</i> 4,[5],12:i:- in Guangdong, China."],"pmcid":["PMC11237462"],"funding_grant_id":["32273066","2019KCXTD001","C6026-19G","C7003-20G","32121004","2019BT02N054"],"pubmed_authors":["Sun R-Y","Chen K-C","Fang L-X","Dai J-J","Wai Chi Chan E","Liu Y-H","Chen S","Ke B-X","Ke C-W","Sun J","Liao X-P"],"additional_accession":[]},"is_claimable":false,"name":"Antimicrobial resistance and population genomics of emerging multidrug-resistant <i>Salmonella</i> 4,[5],12:i:- in Guangdong, China.","description":"<i>Salmonella</i> 4,[5],12:i:-, a monophasic variant of <i>Salmonella</i> Typhimurium, has emerged as a global cause of multidrug-resistant salmonellosis and has become endemic in many developing and developed countries, especially in China. Here, we have sequenced 352 clinical isolates in Guangdong, China, during 2009-2019 and performed a large-scale collection of <i>Salmonella</i> 4,[5],12:i:- with whole genome sequencing (WGS) data across the globe, to better understand the population structure, antimicrobial resistance (AMR) genomic characterization, and transmission routes of <i>Salmonella</i> 4,[5],12:i:- across Guangdong. <i>Salmonella</i> 4,[5],12:i:- strains showed broad genetic diversity; Guangdong isolates were found to be widely distributed among the global lineages. Of note, w","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jun","modification":"2026-06-01T07:34:59.401Z","creation":"2025-04-07T12:05:20.872Z"},"accession":"S-EPMC11237462","cross_references":{"pubmed":["38747582"],"doi":["10.1128/msystems.01164-23"]}}