{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["62(6)"],"submitter":["Dabernig-Heinz J"],"pubmed_abstract":["The environmental bacterium <i>Klebsiella oxytoca</i> displays an alarming increase of antibiotic-resistant strains that frequently cause outbreaks in intensive care units. Due to its prevalence in the environment and opportunistic presence in humans, molecular surveillance (including resistance marker screening) and high-resolution cluster analysis are of high relevance. Furthermore, <i>K. oxytoca</i> previously described in studies is rather a species complex (KoSC) than a single species comprising at least six closely related species that are not easily differentiated by standard typing methods. To reach a discriminatory power high enough to identify and resolve clusters within these species, whole genome sequencing is necessary. The resolution is achievable with core genome multilocus "],"journal":["Journal of clinical microbiology"],"pagination":["e0172523"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11237601"],"repository":["biostudies-literature"],"pubmed_title":["Core genome multilocus sequence typing (cgMLST) applicable to the monophyletic <i>Klebsiella oxytoca</i> species complex."],"pmcid":["PMC11237601"],"pubmed_authors":["Dabernig-Heinz J","Prior K","Ronning TG","Lipp M","Harmsen D","Ruppitsch W","Leitner E","Kienesberger S","Steinmetz I","Wagner GE"],"additional_accession":[]},"is_claimable":false,"name":"Core genome multilocus sequence typing (cgMLST) applicable to the monophyletic <i>Klebsiella oxytoca</i> species complex.","description":"The environmental bacterium <i>Klebsiella oxytoca</i> displays an alarming increase of antibiotic-resistant strains that frequently cause outbreaks in intensive care units. Due to its prevalence in the environment and opportunistic presence in humans, molecular surveillance (including resistance marker screening) and high-resolution cluster analysis are of high relevance. Furthermore, <i>K. oxytoca</i> previously described in studies is rather a species complex (KoSC) than a single species comprising at least six closely related species that are not easily differentiated by standard typing methods. To reach a discriminatory power high enough to identify and resolve clusters within these species, whole genome sequencing is necessary. The resolution is achievable with core genome multilocus ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jun","modification":"2025-04-19T01:04:04.707Z","creation":"2025-04-07T11:57:15.142Z"},"accession":"S-EPMC11237601","cross_references":{"pubmed":["38780286"],"doi":["10.1128/jcm.01725-23"]}}