biostudies-literatureUnknown12Ulrich S<h4>Background</h4>Globally, students face increasing mental health challenges, including elevated stress levels and declining well-being, leading to academic performance issues and mental health disorders. However, due to stigma and symptom underestimation, students rarely seek effective stress management solutions. Conversational agents in the health sector have shown promise in reducing stress, depression, and anxiety. Nevertheless, research on their effectiveness for students with stress remains limited.<h4>Objective</h4>This study aims to develop a conversational agent-delivered stress management coaching intervention for students called MISHA and to evaluate its effectiveness, engagement, and acceptance.<h4>Methods</h4>In an unblinded randomized controlled trial, Swiss students experJMIR mHealth and uHealthe54945https://www.ebi.ac.uk/biostudies/studies/S-EPMC11237786biostudies-literatureA Chatbot-Delivered Stress Management Coaching for Students (MISHA App): Pilot Randomized Controlled Trial.PMC11237786Ulrich SLienhard NKunzli HKowatsch TfalseA Chatbot-Delivered Stress Management Coaching for Students (MISHA App): Pilot Randomized Controlled Trial.<h4>Background</h4>Globally, students face increasing mental health challenges, including elevated stress levels and declining well-being, leading to academic performance issues and mental health disorders. However, due to stigma and symptom underestimation, students rarely seek effective stress management solutions. Conversational agents in the health sector have shown promise in reducing stress, depression, and anxiety. Nevertheless, research on their effectiveness for students with stress remains limited.<h4>Objective</h4>This study aims to develop a conversational agent-delivered stress management coaching intervention for students called MISHA and to evaluate its effectiveness, engagement, and acceptance.<h4>Methods</h4>In an unblinded randomized controlled trial, Swiss students exper2024-01-01T00:00:00Z2024 Jun2025-04-05T15:47:17.419Z2025-04-05T15:47:17.419ZS-EPMC112377863892267710.2196/54945