{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["26(7)"],"submitter":["Zorner CR"],"funding":["Gentofte University Hospital Department of Cardiovascular Research"],"pubmed_abstract":["Aims
The treatment of atrial fibrillation (AF) in hypertrophic cardiomyopathy (HCM) can be challenging since AF aggravates symptoms and increases the risk of stroke. Which factors contribute to the development of AF and stroke in HCM remains unknown. The aim of this study was to determine the incidence of AF and stroke in HCM patients and identify the risk factors.Methods and results
Using Danish national registries, all HCM patients from 2005 to 2018 were included. The association between HCM, incident AF, and stroke was investigated using multivariable Cox proportional hazards analysis. Cumulative incidences were calculated using the Aalen-Johansen estimator. Among the 3367 patients without prevalent AF, 24% reached the endpoint of incident AF with death as a competing ri"],"journal":["Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology"],"pagination":["euae177"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11242463"],"repository":["biostudies-literature"],"pubmed_title":["Understanding the incidence of atrial fibrillation and stroke in hypertrophic cardiomyopathy patients: insights from Danish nationwide registries."],"pmcid":["PMC11242463"],"pubmed_authors":["Zorner CR","Christensen AH","Schjerning AM","Rasmussen PV","Gislason G","Hansen ML","Tfelt-Hansen J","Middelfart C","Riis-Vestergaard LD","Tonnesen J","Jensen MK"],"additional_accession":[]},"is_claimable":false,"name":"Understanding the incidence of atrial fibrillation and stroke in hypertrophic cardiomyopathy patients: insights from Danish nationwide registries.","description":"Aims
The treatment of atrial fibrillation (AF) in hypertrophic cardiomyopathy (HCM) can be challenging since AF aggravates symptoms and increases the risk of stroke. Which factors contribute to the development of AF and stroke in HCM remains unknown. The aim of this study was to determine the incidence of AF and stroke in HCM patients and identify the risk factors.Methods and results
Using Danish national registries, all HCM patients from 2005 to 2018 were included. The association between HCM, incident AF, and stroke was investigated using multivariable Cox proportional hazards analysis. Cumulative incidences were calculated using the Aalen-Johansen estimator. Among the 3367 patients without prevalent AF, 24% reached the endpoint of incident AF with death as a competing ri","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2025-04-27T00:58:32.294Z","creation":"2025-04-06T18:03:40.697Z"},"accession":"S-EPMC11242463","cross_references":{"pubmed":["38917047"],"doi":["10.1093/europace/euae177"]}}