{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Shao L"],"funding":["Wei Wu","Long Shao"],"pagination":["1127"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11243747"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(13)"],"pubmed_abstract":["Highly sensitive and specific biomarker detection is of outstanding importance for the diagnosis and treatment of cancers. Herein, we developed robust photoelectrochemical (PEC) biosensors with low background noise and high sensitivity based on a heterojunction, which can improve semiconductor photoelectric properties by limiting the recombination of photogenerated electron-hole pairs and successfully widening the range of light absorption. Alpha-fetoprotein (AFP) was used as a target model to examine the analytical performances of the designed PEC biosensors. ZnO/Cs<sub>3</sub>MnBr<sub>5</sub> heterogeneous film with a uniform porous structure and large surface area enhanced electron transfer and biomolecule immobilization, and significantly increased the photocurrent response. Under the "],"journal":["Nanomaterials (Basel, Switzerland)"],"pubmed_title":["A Label-Free Photoelectrochemical Biosensor Based on ZnO/Cs<sub>3</sub>MnBr<sub>5</sub> Heterogeneous Films for Alpha-Fetoprotein Detection."],"pmcid":["PMC11243747"],"funding_grant_id":["2021LC131","62305045"],"pubmed_authors":["Liu M","Shao L","Cui G","Wu W","Zhang B"],"additional_accession":[]},"is_claimable":false,"name":"A Label-Free Photoelectrochemical Biosensor Based on ZnO/Cs<sub>3</sub>MnBr<sub>5</sub> Heterogeneous Films for Alpha-Fetoprotein Detection.","description":"Highly sensitive and specific biomarker detection is of outstanding importance for the diagnosis and treatment of cancers. Herein, we developed robust photoelectrochemical (PEC) biosensors with low background noise and high sensitivity based on a heterojunction, which can improve semiconductor photoelectric properties by limiting the recombination of photogenerated electron-hole pairs and successfully widening the range of light absorption. Alpha-fetoprotein (AFP) was used as a target model to examine the analytical performances of the designed PEC biosensors. ZnO/Cs<sub>3</sub>MnBr<sub>5</sub> heterogeneous film with a uniform porous structure and large surface area enhanced electron transfer and biomolecule immobilization, and significantly increased the photocurrent response. Under the ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jun","modification":"2025-04-19T12:37:37.011Z","creation":"2025-04-19T12:37:37.011Z"},"accession":"S-EPMC11243747","cross_references":{"pubmed":["38998732"],"doi":["10.3390/nano14131127"]}}