biostudies-literatureUnknown19(7)Zhang X<h4>Purpose</h4>Patients with cancer often present with a hypercoagulable state, which is closely associated with tumor progression. The purpose of this study was to assess the diagnostic efficacy of D-dimer in predicting distant metastasis in colorectal cancer (CRC).<h4>Methods</h4>This study included 529 patients diagnosed with CRC at our hospital between January 2020 and December 2022. Plasma coagulation indicators and tumor markers were collected prior to treatment and their diagnostic efficacy for predicting CRC metastasis was assessed by receiver operating characteristic (ROC) curves. Independent risk factors for evaluating tumor metastasis were obtained by multivariate logistic regression analysis.<h4>Results</h4>The level of D-dimer in the metastatic group was significantly higher PloS onee0306909https://www.ebi.ac.uk/biostudies/studies/S-EPMC11244829biostudies-literatureEffectiveness of D-dimer in predicting distant metastasis in colorectal cancer.PMC11244829Li WZhang XDiao DDang CWang XLin JfalseEffectiveness of D-dimer in predicting distant metastasis in colorectal cancer.<h4>Purpose</h4>Patients with cancer often present with a hypercoagulable state, which is closely associated with tumor progression. The purpose of this study was to assess the diagnostic efficacy of D-dimer in predicting distant metastasis in colorectal cancer (CRC).<h4>Methods</h4>This study included 529 patients diagnosed with CRC at our hospital between January 2020 and December 2022. Plasma coagulation indicators and tumor markers were collected prior to treatment and their diagnostic efficacy for predicting CRC metastasis was assessed by receiver operating characteristic (ROC) curves. Independent risk factors for evaluating tumor metastasis were obtained by multivariate logistic regression analysis.<h4>Results</h4>The level of D-dimer in the metastatic group was significantly higher 2024-01-01T00:00:00Z20242025-04-27T00:59:54.39Z2025-04-06T18:04:13.282ZS-EPMC112448293899589510.1371/journal.pone.0306909