{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Zhang X"],"funding":["NIGMS NIH HHS"],"pubmed_abstract":["<i>Cis</i>-regulatory elements (CREs) precisely control spatiotemporal gene expression in cells. Using a spatially resolved single-cell atlas of gene expression with chromatin accessibility across ten soybean tissues, we identified 103 distinct cell types and 303,199 accessible chromatin regions (ACRs). Nearly 40% of the ACRs showed cell-type-specific patterns and were enriched for transcription factor (TF) motifs defining diverse cell identities. We identified <i>de novo</i> enriched TF motifs and explored conservation of gene regulatory networks underpinning legume symbiotic nitrogen fixation. With comprehensive developmental trajectories for endosperm and embryo, we uncovered the functional transition of the three sub-cell types of endosperm, identified 13 sucrose transporters sharing t"],"journal":["bioRxiv : the preprint server for biology"],"pagination":["2024.07.03.601616"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11244997"],"repository":["biostudies-literature"],"pubmed_title":["A spatially resolved multiomic single-cell atlas of soybean development."],"pmcid":["PMC11244997"],"funding_grant_id":["T32 GM007103","R00 GM144742"],"pubmed_authors":["Bang S","Schmitz RJ","Minow MAA","Luo Z","Zhang X","Mendieta JP","Marand AP","Jang H","Yan H"],"additional_accession":[]},"is_claimable":false,"name":"A spatially resolved multiomic single-cell atlas of soybean development.","description":"<i>Cis</i>-regulatory elements (CREs) precisely control spatiotemporal gene expression in cells. Using a spatially resolved single-cell atlas of gene expression with chromatin accessibility across ten soybean tissues, we identified 103 distinct cell types and 303,199 accessible chromatin regions (ACRs). Nearly 40% of the ACRs showed cell-type-specific patterns and were enriched for transcription factor (TF) motifs defining diverse cell identities. We identified <i>de novo</i> enriched TF motifs and explored conservation of gene regulatory networks underpinning legume symbiotic nitrogen fixation. With comprehensive developmental trajectories for endosperm and embryo, we uncovered the functional transition of the three sub-cell types of endosperm, identified 13 sucrose transporters sharing t","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2026-04-08T19:45:35.055Z","creation":"2025-04-04T11:42:46.803Z"},"accession":"S-EPMC11244997","cross_references":{"pubmed":["39005400"],"doi":["10.1101/2024.07.03.601616"]}}