biostudies-literatureUnknown19Beaulieu J<h4>Introduction</h4>Cardiac glycosides comprise medications such as digoxin and digitoxin, plants, and even certain toad venoms. Intoxication with cardiac glycosides can lead to hemodynamic instability and cardiac arrest. With this narrative review, our objective was to determine if any therapy used in a near-cardiac arrest state due to cardiac glycoside poisoning could improve survival with favourable functional and neurological outcomes.<h4>Methods</h4>We searched the Medline, PubMed, EMBASE and Cochrane Library databases up to February 2022 for controlled trials, observational studies, and case reports. We reviewed studies if participants were exposed to a cardiac glycoside, had hemodynamic instability, and an intervention was attempted to reverse the toxicity. The effect of interventiResuscitation plus100690https://www.ebi.ac.uk/biostudies/studies/S-EPMC11246064biostudies-literatureAntidote use for cardiac arrest or hemodynamic instability due to cardiac glycoside poisoning: A narrative review.PMC11246064Beaulieu JSt-Onge MfalseAntidote use for cardiac arrest or hemodynamic instability due to cardiac glycoside poisoning: A narrative review.<h4>Introduction</h4>Cardiac glycosides comprise medications such as digoxin and digitoxin, plants, and even certain toad venoms. Intoxication with cardiac glycosides can lead to hemodynamic instability and cardiac arrest. With this narrative review, our objective was to determine if any therapy used in a near-cardiac arrest state due to cardiac glycoside poisoning could improve survival with favourable functional and neurological outcomes.<h4>Methods</h4>We searched the Medline, PubMed, EMBASE and Cochrane Library databases up to February 2022 for controlled trials, observational studies, and case reports. We reviewed studies if participants were exposed to a cardiac glycoside, had hemodynamic instability, and an intervention was attempted to reverse the toxicity. The effect of interventi2024-01-01T00:00:00Z2024 Sep2025-04-18T21:43:56.298Z2025-02-19T02:34:41.97ZS-EPMC112460643900613210.1016/j.resplu.2024.100690