{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(13)"],"submitter":["Dank A"],"pubmed_abstract":["Ethylene glycol (EG, 1,2-ethanediol) is a two-carbon dihydroxy alcohol that can be derived from fermentation of plant-derived xylose and arabinose and which can be formed during food fermentations. Here we show that <i>Propionibacterium freudenreichii</i> DSM 20271 is able to convert EG in anaerobic conditions to ethanol and acetate in almost equimolar amounts. The metabolism of EG led to a moderate increase of biomass, indicating its metabolism is energetically favourable. A proteomic analysis revealed EG induced expression of the <i>pdu</i>-cluster, which encodes a functional bacterial microcompartment (BMC) involved in the degradation of 1,2-propanediol, with the presence of BMCs confirmed using transmission electron microscopy. Cross-examination of the proteomes of 1,2-propanediol and "],"journal":["Heliyon"],"pagination":["e33444"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11255663"],"repository":["biostudies-literature"],"pubmed_title":["Ethylene glycol is metabolized to ethanol and acetate and induces expression of bacterial microcompartments in <i>Propionibacterium freudenreichii</i>."],"pmcid":["PMC11255663"],"pubmed_authors":["Liu Y","Wen X","Boeren S","Lin F","Abee T","Wiersma A","Smid EJ","Dank A","Notebaart RA"],"additional_accession":[]},"is_claimable":false,"name":"Ethylene glycol is metabolized to ethanol and acetate and induces expression of bacterial microcompartments in <i>Propionibacterium freudenreichii</i>.","description":"Ethylene glycol (EG, 1,2-ethanediol) is a two-carbon dihydroxy alcohol that can be derived from fermentation of plant-derived xylose and arabinose and which can be formed during food fermentations. Here we show that <i>Propionibacterium freudenreichii</i> DSM 20271 is able to convert EG in anaerobic conditions to ethanol and acetate in almost equimolar amounts. The metabolism of EG led to a moderate increase of biomass, indicating its metabolism is energetically favourable. A proteomic analysis revealed EG induced expression of the <i>pdu</i>-cluster, which encodes a functional bacterial microcompartment (BMC) involved in the degradation of 1,2-propanediol, with the presence of BMCs confirmed using transmission electron microscopy. Cross-examination of the proteomes of 1,2-propanediol and ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2026-06-01T16:30:01.431Z","creation":"2025-04-04T14:47:12.322Z"},"accession":"S-EPMC11255663","cross_references":{"pubmed":["39027605"],"doi":["10.1016/j.heliyon.2024.e33444"]}}