biostudies-literatureUnknown6(1)Beckonert NMUniversitätsklinikum Bonn<h4>Background</h4>Endovascular treatment (ET) options for acute stroke due to distal middle cerebral artery occlusions are rapidly evolving, but data on outcome and safety are sparse. We therefore performed an analysis of patients undergoing ET for primary M3 occlusions in routine clinical practice in a nationwide registry.<h4>Methods</h4>Patients enrolled between 01/20 and 12/21 in the prospective, multicenter German Stroke Registry-Endovascular Treatment (GSR-ET) were screened for mechanical thrombectomy performed for primary M3 occlusion. We analyzed neurological deficit as measured by the National Institute of Health Stroke Scale (NIHSS), symptomatic intracranial hemorrhage (sICH), thrombectomy technique, successful reperfusion (modified Thrombolysis in Cerebral Infarction [mTICI] scoNeurological research and practice36https://www.ebi.ac.uk/biostudies/studies/S-EPMC11256396biostudies-literatureEndovascular treatment of primary M3 occlusion stroke in clinical practice: analysis of the German Stroke Registry.PMC11256396Bode FJBormann ABraun MStogbauer FKellert LNitsch LAlegiani ACHenn KHDeb-Chatterji MWeller JMBoeckh-Behrens TLudolph ALehnen NCBorggrefe JErnemann UHamann GFPetzold GCBeckonert NMReich ALiman JWunderlich SKeil FPetersen MThomalla GKrause LUTiedt SUphaus TNolte CBohner GErnst MSHattingen JDorn FMuehl-Benninghaus RRiedel CGroschel KSchafer JHPoli SSchell MSchellinger PRother JEckert BKraemer CTrumm CGerloff CBerrouschot JSiebert EGSR-ET investigatorsFiehler JNikoubashman OZweynert SfalseEndovascular treatment of primary M3 occlusion stroke in clinical practice: analysis of the German Stroke Registry.<h4>Background</h4>Endovascular treatment (ET) options for acute stroke due to distal middle cerebral artery occlusions are rapidly evolving, but data on outcome and safety are sparse. We therefore performed an analysis of patients undergoing ET for primary M3 occlusions in routine clinical practice in a nationwide registry.<h4>Methods</h4>Patients enrolled between 01/20 and 12/21 in the prospective, multicenter German Stroke Registry-Endovascular Treatment (GSR-ET) were screened for mechanical thrombectomy performed for primary M3 occlusion. We analyzed neurological deficit as measured by the National Institute of Health Stroke Scale (NIHSS), symptomatic intracranial hemorrhage (sICH), thrombectomy technique, successful reperfusion (modified Thrombolysis in Cerebral Infarction [mTICI] sco2024-01-01T00:00:00Z2024 Jul2026-06-02T22:55:04.831Z2025-04-06T17:11:47.168ZS-EPMC112563963902040910.1186/s42466-024-00330-7