biostudies-literatureKhera NNCI NIH HHS3497-3506https://www.ebi.ac.uk/biostudies/studies/S-EPMC11260842biostudies-literatureUnknown8(13)<h4>Abstract</h4>There has been an increase in volume as well as an improvement in overall survival (OS) after hematopoietic cell transplantation (HCT) for hematologic disorders. It is unknown if these changes have affected racial/ethnic minorities equally. In this observational study from the Center for International Blood and Marrow Transplant Research of 79 904 autologous (auto) and 65 662 allogeneic (allo) HCTs, we examined the volume and rates of change of autoHCT and alloHCT over time and trends in OS in 4 racial/ethnic groups: non-Hispanic Whites (NHWs), non-Hispanic African Americans (NHAAs), and Hispanics across 5 2-year cohorts from 2009 to 2018. Rates of change were compared using Poisson model. Adjusted and unadjusted Cox proportional hazards models examined trends in mortalityBlood advancesTrends in volumes and survival after hematopoietic cell transplantation in racial/ethnic minorities.PMC11260842P30 CA008748U24 CA076518Agrawal VYared JARangarajan HGBallen KHashmi SHossain NMHashem HKhera NCiurea SBadawy SMWood WASharma ABeitinjaneh AMunker RLeMaistre CFAl-Homsi ASPatel JAljurf MPreussler JMLehmann LELazarus HMWinestone LEDiaz Perez MASaber WAilawadhi SFingrut WBCerny JSchears RMSeo SBrazauskas RSteinberg AHahn TKnight JMKelkar AHBhatt NSKindwall-Keller TUstun CArnold SDJacobs BAbid MBSavani BNHong SWirk BfalseTrends in volumes and survival after hematopoietic cell transplantation in racial/ethnic minorities.<h4>Abstract</h4>There has been an increase in volume as well as an improvement in overall survival (OS) after hematopoietic cell transplantation (HCT) for hematologic disorders. It is unknown if these changes have affected racial/ethnic minorities equally. In this observational study from the Center for International Blood and Marrow Transplant Research of 79 904 autologous (auto) and 65 662 allogeneic (allo) HCTs, we examined the volume and rates of change of autoHCT and alloHCT over time and trends in OS in 4 racial/ethnic groups: non-Hispanic Whites (NHWs), non-Hispanic African Americans (NHAAs), and Hispanics across 5 2-year cohorts from 2009 to 2018. Rates of change were compared using Poisson model. Adjusted and unadjusted Cox proportional hazards models examined trends in mortality2024-01-01T00:00:00Z2024 Jul2026-06-02T04:39:22.235Z2025-05-18T13:26:59.202ZS-EPMC112608423866137210.1182/bloodadvances.2023012469