biostudies-literatureLian LNIBIB NIH HHSNHLBI NIH HHSBrigham Research InstituteNational Institutes of HealthChan Zuckerberg InitiativeFoundation for the National Institutes of HealthNCI NIH HHSArmy Research OfficeNIAMS NIH HHSAFOSRAir Force Office of Scientific ResearchNIH HHSARONational Science Foundatione2304846https://www.ebi.ac.uk/biostudies/studies/S-EPMC11260906biostudies-literatureUnknown36(34)Decellularized extracellular matrix (dECM)-based hydrogels are widely applied to additive biomanufacturing strategies for relevant applications. The extracellular matrix components and growth factors of dECM play crucial roles in cell adhesion, growth, and differentiation. However, the generally poor mechanical properties and printability have remained as major limitations for dECM-based materials. In this study, heart-derived dECM (h-dECM) and meniscus-derived dECM (Ms-dECM) bioinks in their pristine, unmodified state supplemented with the photoinitiator system of tris(2,2-bipyridyl) dichlororuthenium(II) hexahydrate and sodium persulfate, demonstrate cytocompatibility with volumetric bioprinting processes. This recently developed bioprinting modality illuminates a dynamically evolving liAdvanced materials (Deerfield Beach, Fla.)Rapid Volumetric Bioprinting of Decellularized Extracellular Matrix Bioinks.PMC11260906CISE-IIS-2225698R01AR070975P41 EB027062R01EB028143CBET‐EBMS‐1936105R01HL166522R01 CA282451R01HL165176P41EB0270621541959R01 EB028143R01 HL165176CBET-EBMS-1936105FA9550‐20‐1‐0363W911NF21201302022‐316712R01 HL166522R01CA282451FA9550-20-1-0363R21EB030257CISE‐IIS‐2225698R01 AR070975R21 EB0302572022-316712Li GMaharjan SSahoo JKMu XKaplan DLLuo ZMei XWang DXie MAbril Manjarrez Rivera VCai LGonzalez FZKuang XTang GLian LGarciamendez-Mijares CEGuo JZhang ZZhang YSfalseRapid Volumetric Bioprinting of Decellularized Extracellular Matrix Bioinks.Decellularized extracellular matrix (dECM)-based hydrogels are widely applied to additive biomanufacturing strategies for relevant applications. The extracellular matrix components and growth factors of dECM play crucial roles in cell adhesion, growth, and differentiation. However, the generally poor mechanical properties and printability have remained as major limitations for dECM-based materials. In this study, heart-derived dECM (h-dECM) and meniscus-derived dECM (Ms-dECM) bioinks in their pristine, unmodified state supplemented with the photoinitiator system of tris(2,2-bipyridyl) dichlororuthenium(II) hexahydrate and sodium persulfate, demonstrate cytocompatibility with volumetric bioprinting processes. This recently developed bioprinting modality illuminates a dynamically evolving li2024-01-01T00:00:00Z2024 Aug2026-03-16T08:18:10.97Z2025-08-15T03:06:17.887ZS-EPMC112609063825289610.1002/adma.202304846