{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Morris SE"],"funding":["Intramural CDC HHS"],"pagination":["1336-1344"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11260992"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["78(5)"],"pubmed_abstract":["<h4>Background</h4>Antiviral chemoprophylaxis is recommended for use during influenza outbreaks in nursing homes to prevent transmission and severe disease among non-ill residents. Centers for Disease Control and Prevention (CDC) guidance recommends prophylaxis be initiated for all non-ill residents once an influenza outbreak is detected and be continued for at least 14 days and until 7 days after the last laboratory-confirmed influenza case is identified. However, not all facilities strictly adhere to this guidance and the impact of such partial adherence is not fully understood.<h4>Methods</h4>We developed a stochastic compartmental framework to model influenza transmission within an average-sized US nursing home. We compared the number of symptomatic illnesses and hospitalizations under"],"journal":["Clinical infectious diseases : an official publication of the Infectious Diseases Society of America"],"pubmed_title":["Modeling the Impacts of Antiviral Prophylaxis Strategies in Mitigating Seasonal Influenza Outbreaks in Nursing Homes."],"pmcid":["PMC11260992"],"funding_grant_id":["CC999999"],"pubmed_authors":["Morris SE","Garg S","Brenner S","Paul P","Biggerstaff M","Zipfel CM","Slayton RB","Peer K","Madewell ZJ"],"additional_accession":[]},"is_claimable":false,"name":"Modeling the Impacts of Antiviral Prophylaxis Strategies in Mitigating Seasonal Influenza Outbreaks in Nursing Homes.","description":"<h4>Background</h4>Antiviral chemoprophylaxis is recommended for use during influenza outbreaks in nursing homes to prevent transmission and severe disease among non-ill residents. Centers for Disease Control and Prevention (CDC) guidance recommends prophylaxis be initiated for all non-ill residents once an influenza outbreak is detected and be continued for at least 14 days and until 7 days after the last laboratory-confirmed influenza case is identified. However, not all facilities strictly adhere to this guidance and the impact of such partial adherence is not fully understood.<h4>Methods</h4>We developed a stochastic compartmental framework to model influenza transmission within an average-sized US nursing home. We compared the number of symptomatic illnesses and hospitalizations under","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 May","modification":"2025-04-04T14:46:07.925Z","creation":"2025-04-04T14:46:07.925Z"},"accession":"S-EPMC11260992","cross_references":{"pubmed":["38072652"],"doi":["10.1093/cid/ciad764"]}}