biostudies-literatureUnknown14(32)Kumar RUniversity of DelhiA novel Schiff base moiety, (<i>E</i>)-4-(1-hydrazonoethyl)benzene-1,3-diol (2), and 2,4-dihydroxybenzaldehyde were condensed in a 1 : 1 molar ratio to generate 4-((<i>E</i>)-1-(((<i>Z</i>)-2,4dihydroxybenzylidene)hydrazono)ethyl)benzene-1,3-diol (L), which was then characterized using high-resolution mass spectrometry (HRMS), ¹H-NMR, ¹³C NMR, and single-crystal XRD techniques. UV-vis absorbance measurements were used to determine whether the Schiff base could detect the cupric ions more effectively than the other transition metal ions. When Cu²⁺ ions were involved, a new band was observed at 462 nm. From the Job plot, the binding stoichiometry for the anticipated L : Cu²⁺ partnership is determined to be 1 : 1. For the purpose of validating strucRSC advances23083-23094https://www.ebi.ac.uk/biostudies/studies/S-EPMC11261578biostudies-literatureAn innovative Schiff-base colorimetric chemosensor for the selective detection of Cu²⁺ ions and its applications.PMC11261578Pani BVerma AKakkar RBhandari MSingh BKumar RGahlyan PfalseAn innovative Schiff-base colorimetric chemosensor for the selective detection of Cu²⁺ ions and its applications.A novel Schiff base moiety, (<i>E</i>)-4-(1-hydrazonoethyl)benzene-1,3-diol (2), and 2,4-dihydroxybenzaldehyde were condensed in a 1 : 1 molar ratio to generate 4-((<i>E</i>)-1-(((<i>Z</i>)-2,4dihydroxybenzylidene)hydrazono)ethyl)benzene-1,3-diol (L), which was then characterized using high-resolution mass spectrometry (HRMS), ¹H-NMR, ¹³C NMR, and single-crystal XRD techniques. UV-vis absorbance measurements were used to determine whether the Schiff base could detect the cupric ions more effectively than the other transition metal ions. When Cu²⁺ ions were involved, a new band was observed at 462 nm. From the Job plot, the binding stoichiometry for the anticipated L : Cu²⁺ partnership is determined to be 1 : 1. For the purpose of validating struc2024-01-01T00:00:00Z2024 Jul2026-06-01T20:30:01.124Z2026-05-20T03:08:17.676ZS-EPMC112615783904069510.1039/d4ra03097d