{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Millen M"],"funding":["Swiss National Science Foundation"],"pagination":["7228-7235"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11261599"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(28)"],"pubmed_abstract":["Magic angle spinning (MAS) dynamic nuclear polarization (DNP) increases the signal intensity of solid-state nuclear magnetic resonance. DNP typically uses continuous wave (CW) microwave irradiation close to the resonance frequency of unpaired electron spins. In this study, we demonstrate that frequency-chirped microwaves improve DNP performance under MAS. By modulating the gyrotron anode potential, we generate a train of microwave chirps with a maximum bandwidth of 310 MHz and a maximum incident power on the spinning sample of 18 W. We characterize the efficiency of chirped DNP using the following polarizing agents: TEMTriPol-1, AsymPolPOK, AMUPol, and Finland trityl. The effects of different chirp widths and periods are analyzed at different MAS frequencies and microwave powers. Furthermo"],"journal":["The journal of physical chemistry letters"],"pubmed_title":["Frequency-Chirped Magic Angle Spinning Dynamic Nuclear Polarization Combined with Electron Decoupling."],"pmcid":["PMC11261599"],"funding_grant_id":["219514","201070"],"pubmed_authors":["Saliba EP","Bjorgvinsdottir S","Pagonakis IG","Alaniva N","Millen M","Sigurdsson ST","Overall SA","Dapp A","Barnes AB"],"additional_accession":[]},"is_claimable":false,"name":"Frequency-Chirped Magic Angle Spinning Dynamic Nuclear Polarization Combined with Electron Decoupling.","description":"Magic angle spinning (MAS) dynamic nuclear polarization (DNP) increases the signal intensity of solid-state nuclear magnetic resonance. DNP typically uses continuous wave (CW) microwave irradiation close to the resonance frequency of unpaired electron spins. In this study, we demonstrate that frequency-chirped microwaves improve DNP performance under MAS. By modulating the gyrotron anode potential, we generate a train of microwave chirps with a maximum bandwidth of 310 MHz and a maximum incident power on the spinning sample of 18 W. We characterize the efficiency of chirped DNP using the following polarizing agents: TEMTriPol-1, AsymPolPOK, AMUPol, and Finland trityl. The effects of different chirp widths and periods are analyzed at different MAS frequencies and microwave powers. Furthermo","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2025-04-04T14:46:44.011Z","creation":"2025-04-04T14:46:44.011Z"},"accession":"S-EPMC11261599","cross_references":{"pubmed":["38975905"],"doi":["10.1021/acs.jpclett.4c01075"]}}