{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(6)"],"submitter":["Walsh CJ"],"funding":["Teagasc","National Health and Medical Research Council","Science Foundation Ireand"],"pubmed_abstract":["Sequence comparison of 16S rRNA PCR amplicons is an established approach to taxonomically identify bacterial isolates and profile complex microbial communities. One potential application of recent advances in long-read sequencing technologies is to sequence entire rRNA operons and capture significantly more phylogenetic information compared to sequencing of the 16S rRNA (or regions thereof) alone, with the potential to increase the proportion of amplicons that can be reliably classified to lower taxonomic ranks. Here we describe <i>GROND</i> (<i>G</i>enome-derived <i>R</i>ibosomal <i>O</i>pero<i>n D</i>atabase), a publicly available database of quality-checked 16S-ITS-23S rRNA operons, accompanied by multiple taxonomic classifications. <i>GROND</i> will aid researchers in analysis of their"],"journal":["Microbial genomics"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11261877"],"repository":["biostudies-literature"],"pubmed_title":["GROND: a quality-checked and publicly available database of full-length 16S-ITS-23S rRNA operon sequences."],"pmcid":["PMC11261877"],"funding_grant_id":["GNT1145631","2020018","SFI/12/RC/2273_P2"],"pubmed_authors":["Walsh CJ","Stinear TP","Kenny JG","Srinivas M","van Sinderen D","Cotter PD"],"additional_accession":[]},"is_claimable":false,"name":"GROND: a quality-checked and publicly available database of full-length 16S-ITS-23S rRNA operon sequences.","description":"Sequence comparison of 16S rRNA PCR amplicons is an established approach to taxonomically identify bacterial isolates and profile complex microbial communities. One potential application of recent advances in long-read sequencing technologies is to sequence entire rRNA operons and capture significantly more phylogenetic information compared to sequencing of the 16S rRNA (or regions thereof) alone, with the potential to increase the proportion of amplicons that can be reliably classified to lower taxonomic ranks. Here we describe <i>GROND</i> (<i>G</i>enome-derived <i>R</i>ibosomal <i>O</i>pero<i>n D</i>atabase), a publicly available database of quality-checked 16S-ITS-23S rRNA operons, accompanied by multiple taxonomic classifications. <i>GROND</i> will aid researchers in analysis of their","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jun","modification":"2025-04-04T14:46:16.629Z","creation":"2025-04-04T14:46:16.629Z"},"accession":"S-EPMC11261877","cross_references":{"pubmed":["38847800"],"doi":["10.1099/mgen.0.001255"]}}