biostudies-literatureQi CNantong UniversityScience and Technology Project of Nantong City23147-23151https://www.ebi.ac.uk/biostudies/studies/S-EPMC11262084biostudies-literatureUnknown14(32)Zn(OTf)₂-catalyzed intra- and intermolecular selenofunctionalization of alkenes was achieved with electrophilic <i>N</i>-phenylselenophthalimide. This method provides straightforward and efficient access to various seleno-substituted heterocycles and vicinal Se heteroatom-disubstituted molecules under mild conditions. This reaction is compatible with various substrates/functional groups, and preliminary studies on the reaction mechanistic were also conducted.RSC advancesZn(OTf)₂-catalyzed intra- and intermolecular selenofunctionalization of alkenes under mild conditions.PMC11262084JC22022097JC2023035KFJN2365Gu YLu ZBao XXiong BQi CLiu GQfalseZn(OTf)₂-catalyzed intra- and intermolecular selenofunctionalization of alkenes under mild conditions.Zn(OTf)₂-catalyzed intra- and intermolecular selenofunctionalization of alkenes was achieved with electrophilic <i>N</i>-phenylselenophthalimide. This method provides straightforward and efficient access to various seleno-substituted heterocycles and vicinal Se heteroatom-disubstituted molecules under mild conditions. This reaction is compatible with various substrates/functional groups, and preliminary studies on the reaction mechanistic were also conducted.2024-01-01T00:00:00Z2024 Jul2025-05-18T13:26:57.814Z2025-05-18T13:26:57.814ZS-EPMC112620843904069610.1039/d4ra04266b