biostudies-literatureUnknown15Gou F<b>Introduction:</b> Akirin as a highly conserved transcription factor, exerts a profound influence on the growth, development, immune response, and reproductive processes in animals. The brown planthopper (BPH), <i>Nilaparvata lugens</i>, a major pest in rice production in Asia, possesses high reproductive capacity, a critical factor contributing to reduced rice yields. The aims of this study were to demonstrate the regulatory role of Akirin in the reproduction of BPH. <b>Methods:</b> In this study, quantitative PCR (qPCR) was used to detect the mRNA expression of genes. RNA interference (RNAi) was used to downregulate the expression of <i>Akirin</i> gene, and RNA sequencing (RNA-seq) was used to screen for differentially expressed genes caused by <i>Akirin</i> downregulation. Hormone conFrontiers in physiology1415746https://www.ebi.ac.uk/biostudies/studies/S-EPMC11264338biostudies-literatureRole of nuclear protein Akirin in the modulation of female reproduction in <i>Nilaparvata lugens</i> (Hemiptera: Delphacidae).PMC11264338Zhang DChen JZhang MChen SGou FfalseRole of nuclear protein Akirin in the modulation of female reproduction in <i>Nilaparvata lugens</i> (Hemiptera: Delphacidae).<b>Introduction:</b> Akirin as a highly conserved transcription factor, exerts a profound influence on the growth, development, immune response, and reproductive processes in animals. The brown planthopper (BPH), <i>Nilaparvata lugens</i>, a major pest in rice production in Asia, possesses high reproductive capacity, a critical factor contributing to reduced rice yields. The aims of this study were to demonstrate the regulatory role of Akirin in the reproduction of BPH. <b>Methods:</b> In this study, quantitative PCR (qPCR) was used to detect the mRNA expression of genes. RNA interference (RNAi) was used to downregulate the expression of <i>Akirin</i> gene, and RNA sequencing (RNA-seq) was used to screen for differentially expressed genes caused by <i>Akirin</i> downregulation. Hormone con2024-01-01T00:00:00Z20242026-05-22T03:11:27.934Z2025-05-18T13:26:16.974ZS-EPMC112643383904521810.3389/fphys.2024.1415746