biostudies-literatureAklepi GNCATS NIH HHSNIMHD NIH HHSNINDS NIH HHS646-659https://www.ebi.ac.uk/biostudies/studies/S-EPMC11265640biostudies-literatureUnknown41(5-6)Eye tracking assessments are clinician dependent and can contribute to misclassification of coma. We investigated responsiveness to videos with and without audio in traumatic brain injury (TBI) subjects using video eye-tracking (VET). We recruited 20 healthy volunteers and 10 unresponsive TBI subjects. Clinicians were surveyed whether the subject was tracking on their bedside assessment. The Coma Recovery Scale-Revised (CRS-R) was also performed. Eye movements in response to three different 30-second videos with and without sound were recorded using VET. The videos consisted of moving characters (a dancer, a person skateboarding, and Spiderman). Tracking on VET was defined as visual fixation on the character and gaze movement in the same direction of the character on two separate occasionsJournal of neurotraumaCovert Tracking to Immersive Stimuli in Traumatic Brain Injury Subjects With Disorders of Consciousness.PMC11265640R01 MD012467R21 NS128326R01 NS040807U24 NS107267K23 NS126577R01 NS029993KL2 TR002737RF1 NS125578UL1 TR002736R01 NS106014R03 NS112760Dietrich WDSarafraz AGhamasaee PSobczak EMerenda ARundek TBolanos Saavedra AKottapally MWalker MFManolovitz BBass DSamano DMassad NO'Phelan KHAklepi GRobayo LEBlandino CFArwari BClaassen JAlkhachroum ADib SfalseCovert Tracking to Immersive Stimuli in Traumatic Brain Injury Subjects With Disorders of Consciousness.Eye tracking assessments are clinician dependent and can contribute to misclassification of coma. We investigated responsiveness to videos with and without audio in traumatic brain injury (TBI) subjects using video eye-tracking (VET). We recruited 20 healthy volunteers and 10 unresponsive TBI subjects. Clinicians were surveyed whether the subject was tracking on their bedside assessment. The Coma Recovery Scale-Revised (CRS-R) was also performed. Eye movements in response to three different 30-second videos with and without sound were recorded using VET. The videos consisted of moving characters (a dancer, a person skateboarding, and Spiderman). Tracking on VET was defined as visual fixation on the character and gaze movement in the same direction of the character on two separate occasions2024-01-01T00:00:00Z2024 Mar2026-06-02T10:24:26.097Z2025-04-07T07:49:06.16ZS-EPMC112656403762474710.1089/neu.2023.0188