{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Fregulia P"],"funding":["This research was supported in part by an appointment to the Agricultural Research Service (ARS) Research Participation Program administered by the Oak Ridge Institute for Science and Education (ORISE) through an interagency agreement between the U.S. Department of Energy (DOE) and the U.S. Department of Agriculture (USDA).","USDA, Agricultural Research Service under National Program 101 Food Animal Production Current Research Information System (CRIS) funds"],"pagination":["16914"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11266570"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(1)"],"pubmed_abstract":["Manipulation of the rumen microbial ecosystem in early life may affect ruminal fermentation and enhance the productive performance of dairy cows. The objective of this experiment was to evaluate the effects of dosing three different types of microbial inoculum on the rumen epithelium tissue (RE) transcriptome and the rumen epimural metatranscriptome (REM) in dairy calves. For this objective, 15 Holstein bull calves were enrolled in the study at birth and assigned to three different intraruminal inoculum treatments dosed orally once weekly from three to six weeks of age. The inoculum treatments were prepared from rumen contents collected from rumen fistulated lactating cows and were either autoclaved (control; ARF), processed by differential centrifugation to create the bacterial-enriched i"],"journal":["Scientific reports"],"pubmed_title":["Microbial inoculum effects on the rumen epithelial transcriptome and rumen epimural metatranscriptome in calves."],"pmcid":["PMC11266570"],"funding_grant_id":["5090-31000-026-00D","DE-SC0014664"],"pubmed_authors":["Li W","Cersosimo LM","Zanton GI","Fregulia P","Park T"],"additional_accession":[]},"is_claimable":false,"name":"Microbial inoculum effects on the rumen epithelial transcriptome and rumen epimural metatranscriptome in calves.","description":"Manipulation of the rumen microbial ecosystem in early life may affect ruminal fermentation and enhance the productive performance of dairy cows. The objective of this experiment was to evaluate the effects of dosing three different types of microbial inoculum on the rumen epithelium tissue (RE) transcriptome and the rumen epimural metatranscriptome (REM) in dairy calves. For this objective, 15 Holstein bull calves were enrolled in the study at birth and assigned to three different intraruminal inoculum treatments dosed orally once weekly from three to six weeks of age. The inoculum treatments were prepared from rumen contents collected from rumen fistulated lactating cows and were either autoclaved (control; ARF), processed by differential centrifugation to create the bacterial-enriched i","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2026-06-01T22:12:10.123Z","creation":"2025-04-19T13:14:32.628Z"},"accession":"S-EPMC11266570","cross_references":{"pubmed":["39043743"],"doi":["10.1038/s41598-024-65685-y"]}}