{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bermingham KM"],"funding":["NIDDK NIH HHS","Medical Research Council","ZOE Ltd"],"pagination":["1888-1897"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11271409"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["30(7)"],"pubmed_abstract":["Large variability exists in people's responses to foods. However, the efficacy of personalized dietary advice for health remains understudied. We compared a personalized dietary program (PDP) versus general advice (control) on cardiometabolic health using a randomized clinical trial. The PDP used food characteristics, individual postprandial glucose and triglyceride (TG) responses to foods, microbiomes and health history, to produce personalized food scores in an 18-week app-based program. The control group received standard care dietary advice (US Department of Agriculture Guidelines for Americans, 2020-2025) using online resources, check-ins, video lessons and a leaflet. Primary outcomes were serum low-density lipoprotein cholesterol and TG concentrations at baseline and at 18 weeks. Par"],"journal":["Nature medicine"],"pubmed_title":["Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial."],"pmcid":["PMC11271409"],"funding_grant_id":["MR/Y010175/1","P30 DK111022","MR/W026813/1"],"pubmed_authors":["Segata N","Bermingham KM","Arre A","Bulsiewicz WJ","Valdes AM","Capdevila J","Hadjigeorgiou G","Delahanty LM","Polidori L","Gardner CD","Asnicar F","Davies R","Linenberg I","Badri F","Berry SE","Hall WL","Spector TD","Wolf J","Ordovas JM","Bernard H"],"additional_accession":[]},"is_claimable":false,"name":"Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial.","description":"Large variability exists in people's responses to foods. However, the efficacy of personalized dietary advice for health remains understudied. We compared a personalized dietary program (PDP) versus general advice (control) on cardiometabolic health using a randomized clinical trial. The PDP used food characteristics, individual postprandial glucose and triglyceride (TG) responses to foods, microbiomes and health history, to produce personalized food scores in an 18-week app-based program. The control group received standard care dietary advice (US Department of Agriculture Guidelines for Americans, 2020-2025) using online resources, check-ins, video lessons and a leaflet. Primary outcomes were serum low-density lipoprotein cholesterol and TG concentrations at baseline and at 18 weeks. Par","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2026-06-02T23:12:21.539Z","creation":"2025-04-19T13:12:24.614Z"},"accession":"S-EPMC11271409","cross_references":{"pubmed":["38714898"],"doi":["10.1038/s41591-024-02951-6"]}}