{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Suemoto CK"],"funding":["NIA NIH HHS"],"pagination":["e2423377"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11273230"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(7)"],"pubmed_abstract":["<h4>Importance</h4>Race differences in dementia prevalence and incidence have previously been reported, with higher dementia burden in Black decedents. However, previous neuropathological studies were conducted mostly in convenience samples with White participants; conducting clinicopathological studies across populations is crucial for understanding the underlying dementia causes in individuals from different racial backgrounds.<h4>Objective</h4>To compare the frequencies of neuropathological lesions and cognitive abilities between Black and White Brazilian adults in an autopsy study.<h4>Design, setting, and participants</h4>This cross-sectional study used samples from the Biobank for Aging Studies, a population-based autopsy study conducted in Sao Paulo, Brazil. Participants were older a"],"journal":["JAMA network open"],"pubmed_title":["Neuropathological Lesions and Cognitive Abilities in Black and White Older Adults in Brazil."],"pmcid":["PMC11273230"],"funding_grant_id":["K24 AG053435","P30 AG062422","R01 AG075802"],"pubmed_authors":["Paes VR","Justo AFO","Nitrini R","Grinberg LT","Pasqualucci CA","Ferriolli E","Naslavsky MS","Leite REP","Jacob-Filho W","Suemoto CK","Zatz M","Rodriguez R"],"additional_accession":[]},"is_claimable":false,"name":"Neuropathological Lesions and Cognitive Abilities in Black and White Older Adults in Brazil.","description":"<h4>Importance</h4>Race differences in dementia prevalence and incidence have previously been reported, with higher dementia burden in Black decedents. However, previous neuropathological studies were conducted mostly in convenience samples with White participants; conducting clinicopathological studies across populations is crucial for understanding the underlying dementia causes in individuals from different racial backgrounds.<h4>Objective</h4>To compare the frequencies of neuropathological lesions and cognitive abilities between Black and White Brazilian adults in an autopsy study.<h4>Design, setting, and participants</h4>This cross-sectional study used samples from the Biobank for Aging Studies, a population-based autopsy study conducted in Sao Paulo, Brazil. Participants were older a","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2026-06-01T22:11:31.285Z","creation":"2025-04-19T13:15:08.194Z"},"accession":"S-EPMC11273230","cross_references":{"pubmed":["39052291"],"doi":["10.1001/jamanetworkopen.2024.23377"]}}