{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Vasilev C"],"funding":["National Defense Education Program","University of Illinois at Urbana-Champaign","European Research Council","Grantham Foundation for the Protection of the Environment","University of Sheffield","National Institutes of Health","Royal Society","NIGMS NIH HHS","Biotechnology and Biological Sciences Research Council","National Science Foundation"],"pagination":["20019-20032"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11273609"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["146(29)"],"pubmed_abstract":["Small, diffusible redox proteins play an essential role in electron transfer (ET) in respiration and photosynthesis, sustaining life on Earth by shuttling electrons between membrane-bound complexes via finely tuned and reversible interactions. Ensemble kinetic studies show transient ET complexes form in two distinct stages: an \"encounter\" complex largely mediated by electrostatic interactions, which subsequently, through subtle reorganization of the binding interface, forms a \"productive\" ET complex stabilized by additional hydrophobic interactions around the redox-active cofactors. Here, using single-molecule force spectroscopy (SMFS) we dissected the transient ET complexes formed between the photosynthetic reaction center-light harvesting complex 1 (RC-LH1) of <i>Rhodobacter sphaeroides<"],"journal":["Journal of the American Chemical Society"],"pubmed_title":["Single-Molecule Detection of the Encounter and Productive Electron Transfer Complexes of a Photosynthetic Reaction Center."],"pmcid":["PMC11273609"],"funding_grant_id":["R01-GM141298","MCB- 1942763","BB/V006630/1","URF\\R1\\191548","HQ0034-21-S-F001","BB/M000265/1","854126","R01 GM141298"],"pubmed_authors":["Hunter CN","Mayneord GE","Vasilev C","Bowie AGM","Johnson MP","Hitchcock A","Pogorelov TV","Martin EC","Singharoy A","Nguyen J"],"additional_accession":[]},"is_claimable":false,"name":"Single-Molecule Detection of the Encounter and Productive Electron Transfer Complexes of a Photosynthetic Reaction Center.","description":"Small, diffusible redox proteins play an essential role in electron transfer (ET) in respiration and photosynthesis, sustaining life on Earth by shuttling electrons between membrane-bound complexes via finely tuned and reversible interactions. Ensemble kinetic studies show transient ET complexes form in two distinct stages: an \"encounter\" complex largely mediated by electrostatic interactions, which subsequently, through subtle reorganization of the binding interface, forms a \"productive\" ET complex stabilized by additional hydrophobic interactions around the redox-active cofactors. Here, using single-molecule force spectroscopy (SMFS) we dissected the transient ET complexes formed between the photosynthetic reaction center-light harvesting complex 1 (RC-LH1) of <i>Rhodobacter sphaeroides<","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2026-06-01T10:03:04.906Z","creation":"2025-04-19T11:32:19.257Z"},"accession":"S-EPMC11273609","cross_references":{"pubmed":["38991108"],"doi":["10.1021/jacs.4c03913"]}}