{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sun B"],"funding":["NHLBI NIH HHS","National Institute of Health (NIH) grants","Renji Hospital School of Medicine Shanghai Jiaotong University","National Natural Science Foundation of China","Science and Technology Commission of Shanghai Municipality Explorer project","Shanghai Municipal Population and Family Planning Commission"],"pagination":["262-270"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11286112"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["45(3)"],"pubmed_abstract":["<h4>Background and purpose</h4>Intracranial plaque enhancement (IPE) identified by contrast-enhanced vessel wall MR imaging (VW-MR imaging) is an emerging marker of plaque instability related to stroke risk, but there was no standardized timing for postcontrast acquisition. We aim to explore the optimal postcontrast timing by using multiphase contrast-enhanced VW-MR imaging and to test its performance in differentiating culprit and nonculprit lesions.<h4>Materials and methods</h4>Patients with acute ischemic stroke due to intracranial plaque were prospectively recruited to undergo VW-MR imaging with 1 precontrast phase and 4 consecutive postcontrast phases (9 minutes and 13 seconds for each phase). The signal intensity (SI) values of the CSF and intracranial plaque were measured on 1 preco"],"journal":["AJNR. American journal of neuroradiology"],"pubmed_title":["Delayed Enhancement of Intracranial Atherosclerotic Plaque Can Better Differentiate Culprit Lesions: A Multiphase Contrast-Enhanced Vessel Wall MRI Study."],"pmcid":["PMC11286112"],"funding_grant_id":["2019NYBSZX01","R01HL162743 and R00HL136883","22TS1400600","82271942; 81801650; 8230070710","20204Y0089;GWVI-11.2-YQ50","R01 HL162743","R00 HL136883"],"pubmed_authors":["Tian J","Li X","Zhang J","Sun B","Zhou Y","Xu J","Wang L","Mossa-Basha M","Zhao H","Zhu C"],"additional_accession":[]},"is_claimable":false,"name":"Delayed Enhancement of Intracranial Atherosclerotic Plaque Can Better Differentiate Culprit Lesions: A Multiphase Contrast-Enhanced Vessel Wall MRI Study.","description":"<h4>Background and purpose</h4>Intracranial plaque enhancement (IPE) identified by contrast-enhanced vessel wall MR imaging (VW-MR imaging) is an emerging marker of plaque instability related to stroke risk, but there was no standardized timing for postcontrast acquisition. We aim to explore the optimal postcontrast timing by using multiphase contrast-enhanced VW-MR imaging and to test its performance in differentiating culprit and nonculprit lesions.<h4>Materials and methods</h4>Patients with acute ischemic stroke due to intracranial plaque were prospectively recruited to undergo VW-MR imaging with 1 precontrast phase and 4 consecutive postcontrast phases (9 minutes and 13 seconds for each phase). The signal intensity (SI) values of the CSF and intracranial plaque were measured on 1 preco","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2025-04-03T23:36:32.595Z","creation":"2025-04-03T23:36:32.595Z"},"accession":"S-EPMC11286112","cross_references":{"pubmed":["38388686"],"doi":["10.3174/ajnr.A8132","10.3174/ajnr.a8132"]}}