biostudies-literatureUnknown10Kim BI<h4>Background</h4>South Korea has implemented a hand, foot, and mouth disease (HFMD) surveillance system since 2009 to monitor incidence trends and identify disease burden. This nationwide surveillance involves a network of approximately 100 pediatric clinics that report all probable and confirmed HFMD cases. Following the COVID-19 pandemic, infectious disease surveillance systems must be evaluated to ensure the effective use of limited public health resources.<h4>Objective</h4>This study aimed to evaluate the HFMD sentinel surveillance system in South Korea from 2017 to 2022, focusing on the transition period after the COVID-19 pandemic.<h4>Methods</h4>We retrospectively reviewed the HFMD sentinel surveillance system from the Korea Disease Control and Prevention Agency using systematic gJMIR public health and surveillancee59446https://www.ebi.ac.uk/biostudies/studies/S-EPMC11287233biostudies-literatureThe Hand, Foot, and Mouth Disease Sentinel Surveillance System in South Korea: Retrospective Evaluation Study.PMC11287233Do HAhn JYoon BAchangwa CKim JCho SKim BIRyu SWon JLee DfalseThe Hand, Foot, and Mouth Disease Sentinel Surveillance System in South Korea: Retrospective Evaluation Study.<h4>Background</h4>South Korea has implemented a hand, foot, and mouth disease (HFMD) surveillance system since 2009 to monitor incidence trends and identify disease burden. This nationwide surveillance involves a network of approximately 100 pediatric clinics that report all probable and confirmed HFMD cases. Following the COVID-19 pandemic, infectious disease surveillance systems must be evaluated to ensure the effective use of limited public health resources.<h4>Objective</h4>This study aimed to evaluate the HFMD sentinel surveillance system in South Korea from 2017 to 2022, focusing on the transition period after the COVID-19 pandemic.<h4>Methods</h4>We retrospectively reviewed the HFMD sentinel surveillance system from the Korea Disease Control and Prevention Agency using systematic g2024-01-01T00:00:00Z2024 Jul2026-03-11T01:27:39.414Z2025-08-12T03:04:54.275ZS-EPMC112872333904582810.2196/59446