{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sudan SK"],"funding":["NCI NIH HHS"],"pagination":["e2421846"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11287389"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(7)"],"pubmed_abstract":["<h4>Importance</h4>Epidemiologic data suggest an association of obesity with breast cancer (BC); however, obesity's contribution to early onset and risk of diagnosis with specific molecular subtypes by race is uncertain.<h4>Objective</h4>To examine the race-specific association of body mass index with early onset and diagnosis of specific molecular subtypes.<h4>Design, setting, and participants</h4>This retrospective cohort study included patients with BC diagnosed between October 1, 2017, and March 31, 2022, at 3 University of South Alabama Mitchell Cancer Institute clinics. Participants were also prospectively enrolled for serum leptin measurement.<h4>Main outcomes and measures</h4>The primary outcome was age at BC onset and specific subtype diagnosis. The secondary outcome was race-spec"],"journal":["JAMA network open"],"pubmed_title":["Obesity and Early-Onset Breast Cancer and Specific Molecular Subtype Diagnosis in Black and White Women: NIMHD Social Epigenomics Program."],"pmcid":["PMC11287389"],"funding_grant_id":["R01 CA231925"],"pubmed_authors":["Poosarla T","Sudan SK","Holliday NP","Sharma A","Davis W","Nelson C","Vikramdeo KS","Singh AP","Singh KP","Singh S","Deshmukh SK","Prodduturvar P"],"additional_accession":[]},"is_claimable":false,"name":"Obesity and Early-Onset Breast Cancer and Specific Molecular Subtype Diagnosis in Black and White Women: NIMHD Social Epigenomics Program.","description":"<h4>Importance</h4>Epidemiologic data suggest an association of obesity with breast cancer (BC); however, obesity's contribution to early onset and risk of diagnosis with specific molecular subtypes by race is uncertain.<h4>Objective</h4>To examine the race-specific association of body mass index with early onset and diagnosis of specific molecular subtypes.<h4>Design, setting, and participants</h4>This retrospective cohort study included patients with BC diagnosed between October 1, 2017, and March 31, 2022, at 3 University of South Alabama Mitchell Cancer Institute clinics. Participants were also prospectively enrolled for serum leptin measurement.<h4>Main outcomes and measures</h4>The primary outcome was age at BC onset and specific subtype diagnosis. The secondary outcome was race-spec","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2026-06-03T00:18:52.869Z","creation":"2026-04-22T03:11:28.399Z"},"accession":"S-EPMC11287389","cross_references":{"pubmed":["39073818"],"doi":["10.1001/jamanetworkopen.2024.21846"]}}