biostudies-literatureUnknown15(3)Tamura RK<h4>Introduction</h4>It is challenging for pregnant women with type 1 diabetes to maintain optimum glucose level to attain good neonatal outcomes. This study evaluated the efficacy of sensor-augmented insulin pump (SAP) with a predictive low-glucose suspend (PLGS) system in pregnant Japanese women with type 1 diabetes.<h4>Materials and methods</h4>SAP with PLGS was used in 11 of the 22 women with type 1 diabetes who delivered between 2011 and 2021 at the two medical institutions in Japan. Glucose management, insulin delivery suspension time (IST) and neonatal outcomes were retrospectively studied.<h4>Results</h4>In SAP with PLGS cases (<i>n</i> = 11), average glycated hemoglobin levels were < 6.5% throughout the pregnancy, and the time in range (TIR, 63-140 mg/dl) was > 70% in the second aDiabetology international447-455https://www.ebi.ac.uk/biostudies/studies/S-EPMC11291783biostudies-literatureA sensor-augmented pump with a predictive low-glucose suspend system could lead to an optimal time in target range during pregnancy in Japanese women with type 1 diabetes.PMC11291783Kodani NTamura RKKajio HItoh HItoh AMeguro SfalseA sensor-augmented pump with a predictive low-glucose suspend system could lead to an optimal time in target range during pregnancy in Japanese women with type 1 diabetes.<h4>Introduction</h4>It is challenging for pregnant women with type 1 diabetes to maintain optimum glucose level to attain good neonatal outcomes. This study evaluated the efficacy of sensor-augmented insulin pump (SAP) with a predictive low-glucose suspend (PLGS) system in pregnant Japanese women with type 1 diabetes.<h4>Materials and methods</h4>SAP with PLGS was used in 11 of the 22 women with type 1 diabetes who delivered between 2011 and 2021 at the two medical institutions in Japan. Glucose management, insulin delivery suspension time (IST) and neonatal outcomes were retrospectively studied.<h4>Results</h4>In SAP with PLGS cases (<i>n</i> = 11), average glycated hemoglobin levels were < 6.5% throughout the pregnancy, and the time in range (TIR, 63-140 mg/dl) was > 70% in the second a2024-01-01T00:00:00Z2024 Jul2025-06-25T03:04:23.389Z2025-06-25T03:04:23.389ZS-EPMC112917833910116310.1007/s13340-024-00716-7