{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ni H"],"funding":["Guangdong Laboratory for Lingnan Modern Agriculture Shenzhen Branch Project","Natural Science Foundation of Guangdong Province","The Major Program of Guangdong Basic and Applied Research"],"pagination":["46"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11291934"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(1)"],"pubmed_abstract":["Preharvest sprouting (PHS) is a serious problem in rice production as it leads to reductions in grain yield and quality. However, the underlying mechanism of PHS in rice remains unclear. In this study, we identified and characterized a preharvest sprouting and seedling lethal (phssl) mutant. The heterozygous phssl/+ mutant exhibited normal plant development, but severe PHS in paddy fields. However, the homozygous phssl mutant was seedling lethal. Gene cloning and genetic analysis revealed that a point mutation in OsABA3 was responsible for the mutant phenotypes. OsABA3 encodes a molybdenum cofactor (Moco) sulfurase. The activities of the sulfureted Moco-dependent enzymes such as aldehyde oxidase (AO) and xanthine dehydrogenase (XDH) were barely detectable in the phssl mutant. As the final "],"journal":["Rice (New York, N.Y.)"],"pubmed_title":["OsABA3 is Crucial for Plant Survival and Resistance to Multiple Stresses in Rice."],"pmcid":["PMC11291934"],"funding_grant_id":["2022A1515012353","AGIS-ZDXM202202","2019B030302006"],"pubmed_authors":["Fang Y","Wu J","Chen J","Ni H","Wang C","Xu C","Wu W","Yan Y","Chen S","Wang K","Tang X"],"additional_accession":[]},"is_claimable":false,"name":"OsABA3 is Crucial for Plant Survival and Resistance to Multiple Stresses in Rice.","description":"Preharvest sprouting (PHS) is a serious problem in rice production as it leads to reductions in grain yield and quality. However, the underlying mechanism of PHS in rice remains unclear. In this study, we identified and characterized a preharvest sprouting and seedling lethal (phssl) mutant. The heterozygous phssl/+ mutant exhibited normal plant development, but severe PHS in paddy fields. However, the homozygous phssl mutant was seedling lethal. Gene cloning and genetic analysis revealed that a point mutation in OsABA3 was responsible for the mutant phenotypes. OsABA3 encodes a molybdenum cofactor (Moco) sulfurase. The activities of the sulfureted Moco-dependent enzymes such as aldehyde oxidase (AO) and xanthine dehydrogenase (XDH) were barely detectable in the phssl mutant. As the final ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2026-06-03T05:36:22.302Z","creation":"2025-05-29T19:07:13.759Z"},"accession":"S-EPMC11291934","cross_references":{"pubmed":["39083143"],"doi":["10.1186/s12284-024-00724-w"]}}