biostudies-literatureUnknown14(1)Chung EThe role of nutritional status as a prognostic factor in patients with Sjögren's syndrome-associated interstitial lung disease (SjS-ILD) is currently unclear. This study aimed to predict the prognosis of patients with SjS-ILD through their nutritional status assessment. In this retrospective observational study, nutritional status was evaluated at the time of diagnosis using body mass index (BMI) and nutritional markers such as controlling nutritional status (CONUT), the Glasgow prognostic score (GPS), and prognostic nutrition index (PNI) for all participants. Receiver operating characteristic (ROC) analyses were performed using BMI and each nutritional marker data to compare the area under the ROC curve (AUC) and find the cutoff value using the maximum Youden index. Kaplan-Meier analysis Scientific reports17842https://www.ebi.ac.uk/biostudies/studies/S-EPMC11294537biostudies-literatureMalnutrition is associated with mortality in Sjogren's syndrome-associated interstitial lung disease.PMC11294537Kim EYKim SYChung EPark YWoo AYong SHLee SHJung JYPark MSKim YSKang YAfalseMalnutrition is associated with mortality in Sjogren's syndrome-associated interstitial lung disease.The role of nutritional status as a prognostic factor in patients with Sjögren's syndrome-associated interstitial lung disease (SjS-ILD) is currently unclear. This study aimed to predict the prognosis of patients with SjS-ILD through their nutritional status assessment. In this retrospective observational study, nutritional status was evaluated at the time of diagnosis using body mass index (BMI) and nutritional markers such as controlling nutritional status (CONUT), the Glasgow prognostic score (GPS), and prognostic nutrition index (PNI) for all participants. Receiver operating characteristic (ROC) analyses were performed using BMI and each nutritional marker data to compare the area under the ROC curve (AUC) and find the cutoff value using the maximum Youden index. Kaplan-Meier analysis 2024-01-01T00:00:00Z2024 Aug2025-04-19T20:47:06.106Z2025-02-19T02:27:25.896ZS-EPMC112945373909028910.1038/s41598-024-68754-4